Experientia

, Volume 41, Issue 8, pp 1047–1048 | Cite as

Stereological analysis of lipofuscin in the central nervous system ofTorpedo marmorata: correlation with superoxide dismutase distribution

  • E. Aloj
  • F. A. Pisanti
Article

Summary

It was observed that superoxide dismutase activity was inversely proportional to the amount of lipofuscin present in the various anatomotopographical areas of theTorpedo marmorata central nervous system. These results support the theory that age pigments are a product of free lipoperoxidation induced by free radicals.

Key words

Lipofuscin age pigments Torpedo marmorata free radicals superoxide dismutase nervous system 

References

  1. 2.
    F.A.P. is a ‘G. Zuccari’, University of Padova, 80/81 Fellow.Google Scholar
  2. 3.
    Donato, H., in: Age Pigments, p. 63. Ed. R. S. Sohal. Elsevier, Amsterdam 1981.Google Scholar
  3. 4.
    Aloj Totaro, E., and Pisanti, F. A., Acta neurol.34 (1979) 322.Google Scholar
  4. 5.
    Aloj Totaro, E., Pisanti, F. A., Russo, P., and Brunetti, P., Annls Soc. r. zool. Belg., in press (1984).Google Scholar
  5. 6.
    Pisanti, F. A., Frascatore, S., Aloj Totaro, E., and Vuttariello, E., Archs Geront. Geriatr.2 (1983) 343.Google Scholar
  6. 7.
    Misra, H. P., and Fridovich, I., J. biol. Chem.247 (1972) 3170.Google Scholar
  7. 8.
    This investigation was conducted at the Zoological Station of Naples. MPI and CNR (Rome) grants are acknowledged.Google Scholar

Copyright information

© Birkhäuser Verlag 1985

Authors and Affiliations

  • E. Aloj
    • 1
  • F. A. Pisanti
    • 1
  1. 1.Insegnamento di Biologia e Zoologia Generale,I Fac. Medicina e ChirurgiaUniversità di NapoliNapoli(Italy)

Personalised recommendations