The endogenous content of noradrenaline (NA) and dopamine (DA) was determined by radioenzymatic assays in three different areas of the occipital (visual) cortex, in normal cats as well as in DA-deafferented animals. The use of HPLC methodology enabled us to detect and measure in addition two metabolites of DA: 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), thus confirming the existence of a DA innervation in this cortical region.
Key wordsOccipital cortex dopamine HVA DOPAC radioenzymatic assays
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