, Volume 42, Issue 11–12, pp 1242–1244 | Cite as

Dopamine in the visual cortex of the cat

  • T. A. Reader
  • L. F. Quesney
Short Communications


The endogenous content of noradrenaline (NA) and dopamine (DA) was determined by radioenzymatic assays in three different areas of the occipital (visual) cortex, in normal cats as well as in DA-deafferented animals. The use of HPLC methodology enabled us to detect and measure in addition two metabolites of DA: 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA), thus confirming the existence of a DA innervation in this cortical region.

Key words

Occipital cortex dopamine HVA DOPAC radioenzymatic assays 


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  1. 3.
    Quesney, L. F., Andermann, F., Lal, S., and Prelevic, S., Neurology30 (1980) 1169.Google Scholar
  2. 4.
    Quesney, L. F., Andermann, F., and Gloor, P., Neurology31 (1981) 1542.Google Scholar
  3. 5.
    Reader, T. A., Ferron, A., Descarries, L., and Jasper, H. H., Brain Res.160 (1979) 217.Google Scholar
  4. 6.
    Reader, T. A., Experientia34 (1978) 1586.Google Scholar
  5. 7.
    Thierry, A. M., Stinus, L., Blanc, G., and Glowinski, J., Brain Res.50 (1973) 230.Google Scholar
  6. 8.
    Jasper, H. H., and Ajmone-Marsan, C., A Stereotaxic Atlas of the Diencephalon of the Cat. National Research Council of Canada, Ottawa 1954).Google Scholar
  7. 9.
    Meikle, T. H., Jr, and Sprague, J. M., Int. Rev. Neurobiol.6 (1964) 149.Google Scholar
  8. 10.
    Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. biol. Chem.193 (1951) 265.Google Scholar
  9. 11.
    Axelrod, J., and Tomchick, R., Biol. Chem.233 (1958) 313.Google Scholar
  10. 12.
    Cuello, A. C., Hiley, R., and Iversen, I. I., J. Neurochem.21 (1973) 1337.Google Scholar
  11. 13.
    Da Prada, M., and Zürcher, G., Life Sci.19 (1976) 1161.Google Scholar
  12. 14.
    Peuler, J. D., and Johnson, G. A., Life Sci.21 (1977) 625.Google Scholar
  13. 15.
    Reader, T. A., de Champlain, J., and Jasper, H. H., Brain Res.111 (1978) 1461.Google Scholar
  14. 16.
    Reader, T. A., J. neural Transm.50 (1981) 13.Google Scholar
  15. 17.
    Felice, L. J., Felice, J. D., and Kissinger, P. T., J. Neurochem.31 (1978) 1461.Google Scholar
  16. 18.
    Uretsky, N. J., and Iversen, L. L., J. Neurochem.17 (1970) 269.Google Scholar
  17. 19.
    Lindvall, O., Björklund, A., Moore, R. Y., and Stenevi, U., Brain Res.81 (1974) 325.Google Scholar
  18. 20.
    Kehr, W., Lindquist, M., and Carlsson, A. J., J. neural Transm.38 (1976) 173.Google Scholar
  19. 21.
    Versteeg, D. H. G., van der Gugten, J., de Jong, W., and Palkovits, M., Brain Res.113 (1976) 565.Google Scholar
  20. 22.
    Jones, B. E., Harper, S. T., and Halaris, A. E., Brain Res.124 (1977) 473.Google Scholar
  21. 23.
    Reader, T. A., Masse, P., and de Champlain, J., Brain Res.177 (1979) 499.Google Scholar
  22. 24.
    Törk, I., and Turner, S., Neurosci. Lett.24 (1981) 215.Google Scholar
  23. 25.
    Berger, B., Verney, C., Alvarez, C., Vigny, A., and Helle, K. B., Neuroscience15 (1985) 983.Google Scholar
  24. 26.
    Doucet, G., and Descarries, L., Soc. Neurosci. Abstr.10 (1984) 422.Google Scholar
  25. 27.
    Lemay, B., Doucet, G., and Descarries, L., Soc. Neurosci. Abstr.11 (1985) 1017.Google Scholar
  26. 28.
    Geffard, M., Kak, O., Onteniente, B., Seguela, P., Le Moal, M., and Delage, M., J. Neurochem.42 (1984) 1593.Google Scholar

Copyright information

© Birkhäuser Verlag 1986

Authors and Affiliations

  • T. A. Reader
    • 1
    • 2
  • L. F. Quesney
    • 1
    • 2
  1. 1.Centre de Recherche en Sciences Neurologiques, Département de PhysiologieUniversité de MontréalMontrealCanada
  2. 2.Montreal Neurological InstituteMcGill UniversityMontrealCanada

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