, Volume 38, Issue 2, pp 257–258 | Cite as

The effects of phenoxybenzamine on the aortic pressure-diameter relationship in dogs

  • D. N. Stone
  • J. -P. L. Dujardin


The normalized diameter (D/D13.3 where D13.3 equals D at 13.3 kPa under control conditions) was measured at selected pressure levels under different hemodynamic conditions. Hemorrhage caused the normalized diameter to decrease (−3.3%) when compared to control values at a given pressure. Volume expansion anda-blockade with phenoxybenzamine caused D/D13.3 to increase (+3.3% and +8.5% respectively).


Pressure Level Volume Expansion Hemodynamic Condition Phenoxybenzamine 
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Copyright information

© Birkhäuser Verlag 1982

Authors and Affiliations

  • D. N. Stone
    • 1
  • J. -P. L. Dujardin
    • 1
  1. 1.Department of PhysiologyThe Ohio State UniversityColumbusUSA

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