Experientia

, Volume 39, Issue 10, pp 1131–1132 | Cite as

Dopamine vasodilates human cerebral artery

Short Communications Pharmacology, Toxicology

Summary

In human large pial arteries, dopamine-induced relaxations appear to be mediated via dopaminergic receptors, and predominate over contractions mediated via alpha-adrenoceptors.

Keywords

Dopamine Cerebral Artery Dopaminergic Receptor Pial Artery Human Cerebral Artery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Goldberg, L.I., Pharm. Rev.24 (1972) 1.Google Scholar
  2. 2.
    Goldberg, L.I., and Toda, N., Circulation Res. suppl.36 and37 (1975) 1.Google Scholar
  3. 3.
    Toda, N., and Goldberg, L.I., Cardiovasc. Res.9 (1975) 384.Google Scholar
  4. 4.
    Toda, N., Hojo, M., Sakae, K., and Usui, H., Blood Vessels12 (1975) 290.Google Scholar
  5. 5.
    Schmidt, M., and Imbs, J.L., J. cardiovasc. Pharmac.2 (1980) 595.Google Scholar
  6. 6.
    Brodde, O.-E., Meyer, F.-J., Schemuth, W., and Freistuhler, J., Archs Pharmac.316 (1981) 24.Google Scholar
  7. 7.
    Hilditch, A., and Drew, G.M., Eur. J. Pharmac.72 (1981) 287.Google Scholar
  8. 8.
    Toda, N., Br. J. Pharmac.58 (1976) 121.Google Scholar
  9. 9.
    Edvinsson, L., Hardebo, J.E., McCulloch, J., and Owman, Ch., Acta physiol. scand.104 (1978) 349.Google Scholar
  10. 10.
    Kwak, S., and Nakamura, H., in: Cerebral Ischemia — An Update-, p. 179. Eds Z. Ito, T. Kutsuzawa and N. Yasui. Excerpta Medica, Amsterdam 1983.Google Scholar
  11. 11.
    Toda, N., Am. J. Physiol.243 (1982) H145.Google Scholar
  12. 12.
    Toda, N., J. Pharmac. exp. Ther.191 (1974) 139.Google Scholar
  13. 13.
    Toda, N., and Hatano, Y., Eur. J. Pharmac.57 (1979) 231.Google Scholar
  14. 14.
    Ueda, S., Yano, S., and Sakanashi, M., J. Cardiovasc. Pharmac.4 (1982) 76.Google Scholar
  15. 15.
    Jonson, G.A., Baker, C.A., and Smith, R.T., Life Sci.26 (1980) 1591.Google Scholar

Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • N. Toda
    • 1
  1. 1.Department of PharmacologyShiga University of Medical SciencesSeta, Ohtsu(Japan)

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