Experientia

, Volume 32, Issue 8, pp 975–976 | Cite as

Electron-microscopic mapping of the hinge region of myosin

  • Murray Vernon King
Specialia Chimica, Biochimica

Summary

The trypsin-sensitive sites in the labile hinge region of the myosin molecule are located with heightened accuracy (±2 nm) by electron microscopy as lying at 70, 85, 95, and 103 nm from the C-terminus of the rod section of the molecule.

Keywords

Microscopy Electron Microscopy Hinge Region Myosin Molecule Heighten Accuracy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature

  1. 3.
    E. Mihályi andA. G. Szent-Györgyi, J. biol. Chem.201, 189 (1953).PubMedGoogle Scholar
  2. 4.
    J. Gergely, M. A. Gouvea, andD. Karibian, J. biol. Chem.212, 165 (1955).PubMedGoogle Scholar
  3. 5.
    W. R. Middlebrook, Science130, 621 (1959).Google Scholar
  4. 6.
    D. R. Kominz, E. R. Mitchell, T. Nihei, andC. M. Kay, Biochemistry4, 2373 (1965).CrossRefGoogle Scholar
  5. 7.
    S. Lowey, H. S. Slayter, A. G. Weeds, andH. Baker, J. molec. Biol.42, 1 (1969).CrossRefPubMedGoogle Scholar
  6. 8.
    M. Burke, S. Himmelfarb, andW. F. Harrington, Biochemistry12, 701 (1973).CrossRefPubMedGoogle Scholar
  7. 9.
    F. Pepe, J. molec. Biol.27, 227 (1967).CrossRefPubMedGoogle Scholar
  8. 10.
    H. Huxley, Science164, 1356 (1969).PubMedGoogle Scholar
  9. 11.
    E. F. Woods, S. Himmelfarb, andW. F. Harrington, J. biol. Chem.238, 2374 (1963).PubMedGoogle Scholar
  10. 12.
    D. M. Segal, S. Himmelfarb, andW. F. Harrington, J. biol. Chem.242, 1241 (1967).PubMedGoogle Scholar
  11. 13.
    M. Young, M. H. Blanchard, andD. Brown, Proc. natn. Acad. Sci. USA61, 1087 (1968).Google Scholar
  12. 14.
    W. W. Kielley andL. B. Bradley, J. biol. Chem.218, 653 (1956).PubMedGoogle Scholar
  13. 15.
    E. G. Richards, C. S. Chung, D. B. Menzel, andH. S. Olcott, Biochemistry6, 528 (1967).CrossRefPubMedGoogle Scholar
  14. 16.
    M. V. King andM. Young, J. molec. Biol.63, 539 (1972).CrossRefPubMedGoogle Scholar

Copyright information

© Birkhäuser-Verlag 1976

Authors and Affiliations

  • Murray Vernon King
    • 1
    • 2
    • 3
  1. 1.Departments of Biological Chemistry and MedicineHarvard Medical SchoolBostonUSA
  2. 2.the Massachusetts General HospitalBostonUSA
  3. 3.Memorial InstituteBuffaloUSA

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