Experientia

, Volume 34, Issue 9, pp 1216–1217

Effect of vitamin E on post irradiation death in mice

  • M. A. Malick
  • R. M. Roy
  • J. Sternberg
Article

Summary

The 30-day survival after exposure to 800 Rad60Co gamma radiation has been compared for female mice maintained on vitamin E deficient, vitamin E supplemented or regular lab rations before and/or after irradiation. Pre- or post-irradiation dietary supplementation had no effect on survival; however, injection ofa-tocopherol immediately after irradiation significantly reduced radiation lethality.

References

  1. 3.
    L. Tappel, Fedn Proc.24, 73 (1965).Google Scholar
  2. 4.
    F. Masugi and T. Nakamura, Int. J. Vitamin Nutr. Res.46, 188 (1976).Google Scholar
  3. 5.
    C.K. Chow, K. Reddy and A.L. Tappel, J. Nutr.103, 618 (1973).PubMedGoogle Scholar
  4. 6.
    R.E. Serfass and H.E. Ganther, Life. Sci.19, 1139 (1976).PubMedGoogle Scholar
  5. 7.
    R.H. Heinzerling, R.P. Tengerdy, L.L. Wick and D.C. Leuker, Infect. Immun.10, 1292 (1974).PubMedGoogle Scholar
  6. 8.
    P.P. Nair, Proc. 9th int. Congr. Nutr. Mexico 1972, vol. 1, p. 61. 1975.Google Scholar
  7. 9.
    J. Schroeder, Biochim. biophys. Acta343, 173 (1974).PubMedGoogle Scholar
  8. 10.
    D. Lussier and R.M. Roy, Radiat. Res.70, 236 (1977).PubMedGoogle Scholar
  9. 11.
    J. Sternberg, and E. Pascoe-Dawson, Can. med. Ass. J.80, 266 (1959).PubMedGoogle Scholar
  10. 12.
    J.W. Hauswirth and P.P. Nair, Ann. N.Y. Acad. Sci.203, 111 (1972).PubMedGoogle Scholar
  11. 13.
    K. Sakamoto and M. Sakka, Br. J. Radiol.46, 538 (1973).PubMedGoogle Scholar
  12. 14.
    E.W. Prince and J.B. Little, Radiat. Res.53, 49 (1973).PubMedGoogle Scholar
  13. 15.
    U.K. Alekperov, Genetika10, 882 (1974).Google Scholar
  14. 16.
    U.K. Alekperov, and D.D. Akundova, Genetika,10, 12 (1974).Google Scholar
  15. 17.
    A. Hoffer and R.M. Roy, Radiat. Res.61, 439 (1975).PubMedGoogle Scholar
  16. 18.
    T.J. Haley, E.F. McCulloh and W.G. McCormick, Science119, 126 (1954).Google Scholar
  17. 19.
    R. Kobric and R.M. Roy, Experientia33, 959 (1972).Google Scholar
  18. 20.
    H.L. Newmark, W. Pool, J.D. Baurnfeind and E. DeRitter, Pharm. Sci.64, 665 (1975).Google Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • M. A. Malick
    • 1
  • R. M. Roy
    • 1
  • J. Sternberg
    • 1
  1. 1.Department of Biological SciencesConcordia UniversityMontreal(Canada)
  2. 2.Hygiène des milieuxUniversité de MontréalMontréal(Canada)

Personalised recommendations