, Volume 52, Issue 1, pp 5–13 | Cite as

The history of cyclosporin A (Sandimmune®) revisited: Another point of view

  • H. F. Stähelin


The immunosuppressant cyclosporin A (Sandimmune®) has become the first line treatment for preventing rejection of transplanted organs and for certain, autoimmune diseases. The discovery of that drug and its preclinical development are described, and it is shown that most earlier accounts of the history of this compound are, in important respects, incorrect and misleading.

Key words

Cyclosporin A Sandimmune® ovalicin cytochalasin fungus metabolites history discovery 


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© Birkhäuser Verlag Basel 1996

Authors and Affiliations

  • H. F. Stähelin
    • 1
  1. 1.Basel(Switzerland)

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