, Volume 33, Issue 4, pp 533–534 | Cite as

Experimental allergic encephalomyelitis (EAE)-changes in structure and proliferation in rat lymph nodes after sensitization with guinea-pig and bovine basic myelin protein

  • I. Matouš-Malbohan
  • V. Mareš
  • Z. Lodin
  • M. Holub


Substantial difference in the proliferation of lymphoid cells in the draining LN was found in rats injected with guinea-pig EBP-FCA and bovine NBP-FCA indicating significance of the encephalitogenic determinant in the myelin basic protein in the peripheral lymphatic reaction initiating EAE.


Lymph Node Lymphoid Cell Basic Myelin Protein Basic Protein Encephalomyelitis 
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    R. M. Condie, in: Biology of Myelin, p. 321. Ed. R. S. Korey, Harper/Hoeber, New York 1959.Google Scholar
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    I. Matouš-Malbohan, M. Holub, J. Krásenská, V. Mareš and Z. Lodin, Cell. Immun.12, 350 (1974).Google Scholar

Copyright information

© Birkhäuser Verlag 1977

Authors and Affiliations

  • I. Matouš-Malbohan
    • 1
  • V. Mareš
    • 2
  • Z. Lodin
    • 2
  • M. Holub
    • 3
  1. 1.Department of Clinical Immunology of the Charles UniversityFaculty of General MedicinePraha(Czechoslovakia)
  2. 2.Institute of PhysiologyCzechoslovak Academy of SciencesPraha(Czechoslovakia)
  3. 3.Institute of Clinical and Experimental MedicinePraha(Czechoslovakia)

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