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Experientia

, Volume 30, Issue 4, pp 405–405 | Cite as

1,2-Benzisoxazole-3-acetamidoxime hydrochloride, a new psychotropic agent

  • M. Shimizu
  • K. Yoshida
  • T. Karasawa
  • M. Masuda
  • M. Oka
  • T. Ito
  • C. Kamei
  • M. Hori
  • Y. Sohji
  • K. Furukawa
Specialia

Keywords

Imipramine Methamphetamine Tyramine Amantadine Chlorhydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Résumé

Le PF-257 ou chlorhydrate de benzisoxalzole-1,2 acétamidoxime-3 produit des effets variés sur le système nerveux central des animaux. Le profil pharmacologique et l'action fondamentale de cet agent paraissent nouveaux, comparés à ceux des psychotropiques actuels.

References

  1. 1.
    S. Garattini andL. J. Valzelli, J. Pharm. Pharmac.14, 509 (1962).CrossRefGoogle Scholar
  2. 2.
    F. Sulser, J. Watts andB. B. Brodie, Ann. N.Y. Acad. Sci.96, 279 (1962).CrossRefPubMedGoogle Scholar
  3. 3.
    K. Voith andF. Herr, Archs int. Pharmacodyn.182, 318 (1969).Google Scholar
  4. 4.
    P. S. J. Spencer, inAntidepressant Drugs (Eds.S. Garattini andM. N. G. Dukes; Excepta Medica, Amsterdam 1966), p. 194.Google Scholar
  5. 5.
    R. M. Quinton, Br. J. Pharmac.21, 51 (1963).Google Scholar
  6. 6.
    S. H. Snyder andJ. T. Coyle, J. Pharmac. exp. Ther.165, 78 (1969).Google Scholar
  7. 7.
    G. Bartholini, H. M. Bates, W. P. Burkard andA. Pletscher, Nature, Lond.215, 852 (1967).CrossRefGoogle Scholar
  8. 8.
    B. B. Brodie, E. Costa, A. Dlabac, N. H. Neff andH. H. Smookler, J. Pharmac. exp. Ther.154, 493 (1966).Google Scholar

Copyright information

© Birkhäuser Verlag 1974

Authors and Affiliations

  • M. Shimizu
    • 1
  • K. Yoshida
    • 1
  • T. Karasawa
    • 1
  • M. Masuda
    • 1
  • M. Oka
    • 1
  • T. Ito
    • 1
  • C. Kamei
    • 1
  • M. Hori
    • 1
  • Y. Sohji
    • 1
  • K. Furukawa
    • 1
  1. 1.Research LaboratoriesDainippon Pharmaceutical Co., Ltd.Suita, OsakaJapan

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