, Volume 33, Issue 11, pp 1487–1489 | Cite as

Effects of palytoxin on the electrical activity of dog and rabbit heart

  • S. Weidmann


Reversible effects of palytoxin, extracted from colonies of the soft coralPalythoa caribaeorum, are described. There is a decrease of both membrane resting potential and overshoot during activity. Rise time of the action potential is prolonged, while repolarization is shortened. The electrical events resemble those seen with metabolic poisons.


Reversible Effect Electrical Activity Rise Time Rabbit Heart Electrical Event 
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Copyright information

© Experientia 1977

Authors and Affiliations

  • S. Weidmann
    • 1
  1. 1.Department of PharmacologyUniversity of Puerto Rico, Medical Sciences CampusPuerto RicoUSA

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