Neuroscience Translations

, Volume 2, Issue 3, pp 768–774 | Cite as

Mechanism of stimulation of the olfactory receptors in fish

  • L. A. Nazarov
Article
  • 31 Downloads

Summary

  1. 1.

    Irrigation of the olfactory epithelium of fish with solutions of vanillin (an adequate stimulus) or acetylcholine (ACh) resulted in constant and identical changes in unit activity of the olfactory bulb, consisting of an activation of mitral neurons and their axons.

     
  2. 2.

    Single unit responses of the olfactory bulb recorded to such low concentrations of ACh (10−10 g/ml) suggest high sensitivity of the olfactory receptors to this particular stimulus.

     
  3. 3.

    Eserine, a cholinesterase inhibitor, when applied to the olfactory epithelium of fish has a biphasic action. In low concentration it not only causes excitation of the olfactory receptors, but also definitely potentiates the action of an adequate stimulus or of ACh. In high concentration, on the other hand, eserine sharply depresses excitability of the receptors.

     
  4. 4.

    It can thus be concluded that the acetylcholine-cholinesterase system participates in the mechanism of stimulation of receptors of the olfactory epithelium by an odoriferous substance in fish just as in amphibians.

     

Keywords

Acetylcholine Olfactory Bulb Cholinesterase Unit Activity Single Unit 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Kluwer Academic Publishers 1968

Authors and Affiliations

  • L. A. Nazarov
    • 1
  1. 1.Department of Bionic Aspects of Measurements, Institute of Automation and Electrometry, Siberian DivisionUSSR Academy of SciencesNovosibirsk

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