Advertisement

Pharmacy World and Science

, Volume 17, Issue 5, pp 172–176 | Cite as

Cost-evaluation model for clinical trials in a hospital pharmacy service

  • A. Idoate
  • A. Ortega
  • F. J. Carrera
  • A. Aldaz
  • J. Giráldez
Practice/Case Reports

Abstract

A cost-evaluation model was applied to clinical trial protocols to estimate their cost for the hospital pharmacy service. The steps taken in the drug management of clinical research were identified. Fixed costs (common to all clinical trials) and variable costs (peculiar to each clinical trial) were determined for each step. The number of patients, the number of operations, the planned services (receptions, storage, drug dispensing), the timing and difficulty of the study (randomization) were included in the variable costs. The economic assessment of these items was based on the costs of the materials and means used, the cost of staff time and finally the cost of drug storage during the clinical trial. This model was applied to 24 clinical trials carried out in the University Clinic of Navarra. 83% of all pharmacy costs of a clinical trial were variable. Drug dispensing, stock management and return drugs account for 94% of the time expended. The approximate cost of the pharmacy providing investigational services was $1,766 per trial or $174 per patient. Drug storage costs were not an important source of expenditure among the variable costs (7.4%). The best way to determine the cost of a trial is to calculate the number of operations.

Keywords

Clinical trials Cost allocation Drug management Drugs, Investigational Pharmacy service, hospital 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Idoate A, Giráldez J, Jiménez-Torres NV, Tamés MJ, Inaraja MT, Aldaz A. Participación actual del farmacéutico de hospital en los ensayos clínicos de España [Current participation of hospital pharmacists in clinical trials in Spain]. Revista AEFH 1989;1:5–12.Google Scholar
  2. 2.
    Ministerio de Sanidad y Consumo. Real Decreto 561/1993, del 16 de Abril, por el que se establecen los requisitos para la realización de ensayos clínicos con medicamentos [Requirements for developing clinical trials with drugs]. Bol Of Estado 1993 May 13, nr. 114.Google Scholar
  3. 3.
    Swartz AJ. Reimbursement for involvement in investigational drug protocols. Am J Hosp Pharm 1989;46:1334.Google Scholar
  4. 4.
    Anandan JV, Isopi MJ, Warren AJ. Fee structure for investigational drug studies. Am J Hosp Pharm 1993;50:2339–43.PubMedGoogle Scholar

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1995

Authors and Affiliations

  • A. Idoate
    • 1
  • A. Ortega
    • 1
  • F. J. Carrera
    • 1
  • A. Aldaz
    • 1
  • J. Giráldez
    • 1
  1. 1.Department of PharmacyUniversity Clinic of NavarraPamplonaSpain

Personalised recommendations