The effects of naturally deoxynivalenol-contaminated oats on the clinical condition, blood parameters, performance and carcass composition of growing pigs
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A feeding trial with naturally deoxynivalenol (DON)-contaminated oats included in feed mixtures at graded levels was conducted in growing pigs. The DON concentrations were 0, 0.7, 1.7, and 3.5 mg/kg of complete feed mixture givenad libitum to different groups. The data recorded were feed consumption, body weight gain, slaughter weight, biochemical and haematological data including serum immunoglobulin A, clinical condition and post-mortem pathology including histopathology.
Significantly decreasing body weight gain throughout the experimental period, decreased slaughter weight and reduced feed utilization efficiency were observed for the group fed a diet containing 3.5 mg/kg of DON. At the same DON concentration, there were increased liver weights and decreased concentrations of serum protein and albumin, and a temporary fall in packed blood cell volume, serum calcium and serum phosphorus. For the groups fed diets containing 1.7 and 3.5 mg/kg of DON, a statistically significant, dose-related decrease in daily feed consumption was observed. No other effects on haematological, biochemical or immunological parameters were recorded. The carcass quality was not affected in any group.
It was concluded that significant effects in growing pigs may be observed at a dietary DON concentration of 1.7 mg/kg, originating from naturally contaminated oats included in a diet that was otherwise adequate and contained only minor traces of other mycotoxins.
Keywordsdeoxynivalenol mycotoxin oats pathology pig trichothecenes
high-pressure liquid chromatography
nutrient-free sporulation agar
potato dextrose agar
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- Beasly, V.R., 1989. In:Trichothecene Mycotoxicosis: Pathophysiologic Effects, vol. I, (CRC Press, Boca Raton, FL)Google Scholar
- Bergsjø, B., Matre, T. and Nafstad, I., 1992. Effects of diets with graded levels of deoxynivalenol on performance in growing pigs.Journal of Veterinary Medicine,A39, 752–758Google Scholar
- Chavez, E.R., 1984. Vomitoxin-contaminated wheat in pig diets: Pregnant and lactating gilts and weaners.Canadian Journal of Animal Science,64, 717–723Google Scholar
- Chelkowski, J., 1989. In:Fusarium, Mycotoxins, Taxonomy and Pathogenicity. Topics in Secondary Metabolites, vol. 2, (Elsevier, Amsterdam)Google Scholar
- Friend, D.H., Trenholm, H.L., Thompson, B.K., Fiser, P.S. and Hartin, K.E., 1986. Effect of feeding diets containing deoxynivalenol (vomitoxin)-contaminated wheat or corn on the feed consumption, weight gain, organ weight and sexual development of male and female pigs.Canadian Journal of Animal Science,66, 765–775Google Scholar
- Hansson, I., Lundstrøm, K. and Bjärstorp, G., 1986. Simultaneous grading and meat quality measurements by the Hennesy Grading System.The 32nd European Meeting of Meat Research Workers, Ghent, 1986Google Scholar
- Langseth, W., Gullord, M. and Høie, R., 1992. The influence of climatic conditions on formation of trichothecenes in different oat cultivars in Norway. AtThe VIII International IUPAC Symposium on Mycotoxins and Phycotoxins, Mexico, November 1992 [not published]Google Scholar
- Langseth, W., Ellingsen, Y., Nymoen, U. and Økland, E.M., 1989. High-performance liquid chromatographic determination of zearalenone and ochratoxin A in cereals and feed.Journal of Chromatography,478, 269–274Google Scholar
- Liao, L.L., Grollman, A.P. and Horrwitz, S.B., 1976. Mechanism of the action of the 12,13-epoxytrichothecene anguidine: an inhibitor of protein synthesis.Biochimica et Biophysica Acta,452(2, 273–284Google Scholar
- Nelson, P.E., Tousson, T.A. and Marasas, W.F.O., 1983. In:Fusarium Species: An Illustrated Manual for Identification, (The Pennsylvania University Press, University Park of London)Google Scholar
- SAS, 1985.SAS Users Guide: Statistics, (SAS Institute Inc., Cary, NC)Google Scholar
- Schuh, M., Leibetseder, J. and Glawischnig, E., 1982. Chronic effects of different levels of deoxynivalenon (vomitoxin) on weight gain, feed consumption, blood parameters, pathological as well as histopathological changes in fattening pigs.V International IUPAC Symposium on Mycotoxins and Phycotoxins, Vienna, 1982Google Scholar
- Stenwig, H., Langseth, W. and Sandli, D., 1992. The occurrence of trichothecenes and moulds in samples of barley and oats from Norway.Mycotoxin Research, 34th European Seminar on Fusarium, Poland, Sept., 1992Google Scholar
- Sundheim, L., Nagayama, S., Kawamura, O., Tanaka, T., Brodal, G. and Ueno, O., 1988. Trichothecenes and zearalenone in Norwegian barley and wheat.Norwegian Journal of Agricultural Sciences,2, 49–59Google Scholar
- Ueno, Y., 1983. In:Trichothecenes, Chemical, Biological and Toxicological Aspects, Development in Food Science, vol. 4, (Elsevier, Amsterdam)Google Scholar
- Wei, C.M. and Maclaughlin, C.S., 1974. Structure-function relationship in the 12,13-epoxytrichothecenes (novel inhibitors of protein synthesis).Biochemical and Biophysical Research Communication,57, 838Google Scholar