Clinical Autonomic Research

, Volume 3, Issue 4, pp 261–269 | Cite as

Spectral analysis of heart rate in vasovagal syncope: The autonomic nervous system in vasovagal syncope

  • A. Baharav
  • M. Mimouni
  • T. Lehrman-Sagie
  • S. Izraeli
  • S. Akselrod
Research Paper

Abstract

Spectral analysis of heart rate fluctuations was used to investigate the role of the autonomic nervous system in the pathogenesis of vasovagal syncope. Nine adolescents with a history of at least three episodes of vasovagal syncope and nine age-matched healthy controls were studied. All subjects were tested in supine position and at a 60° inclination for 60 min or less if syncope developed. Blood pressure and heart rate were measured, while the ECG and respiration traces were recorded on magnetic tape for later spectral analysis.

Baseline heart rate was lower in control subjects than in patients, increased with tilt in both groups, and remained lower in the control subjects throughout the experiment. Baseline systolic and diastolic blood pressure was similar in both groups. Diastolic blood pressure initially increased with tilt in all subjects and decreased significantly thereafter in patients. Pulse pressure was lower in patients throughout the experiment.

The heart rate power spectra displayed a higher baseline level of low frequency fluctuations in the control group. The high frequency fluctuations component was similar in all subjects. The results of the test, regarding haemodynamic parameters and autonomic control of the heart rate, as expressed by low and high frequency fluctuations, are consistent with a reduced sympathetic reserve in the individuals with previous episodes of syncope.

Key words

Autonomic nervous system Fainting Heart rate fluctuations Spectral analysis Tilt Vasovagal syncope 

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Copyright information

© Rapid Communications of Oxford Ltd. 1993

Authors and Affiliations

  • A. Baharav
    • 2
  • M. Mimouni
    • 2
  • T. Lehrman-Sagie
    • 2
  • S. Izraeli
    • 2
  • S. Akselrod
    • 1
  1. 1.Department of Medical Physics, School of Physics and Astronomy, Sackler Faculty of Exact SciencesTel-Aviv UniversityRamat-AvivIsrael
  2. 2.Department of PediatricsBeilinson Medical CenterPetach TiquaIsrael

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