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Origin of genetically encoded protein synthesis: A model based on selection for RNA peptidation

  • J. Tze-Fei Wong
Article

Abstract

The difficulty in explaining the origin of genetic coding centres on the need to identify selective advantages that could account for the synthesis of peptidyl-tRNA, the essential intermediate in genetically programmed translation. It is resolved by a recognition of the functional advantages derivable from the post-transcriptional addition of peptide cofactors to RNA apo-catalysts. This enables the formulation of a theory for the origin of the genetic encoding of protein synthesis by RNA.

Keywords

Peptide Organic Chemistry Geochemistry Protein Synthesis Genetic Code 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1991

Authors and Affiliations

  • J. Tze-Fei Wong
    • 1
  1. 1.Department of BiochemistryHong Kong University of Science & TechnologyHong Kong

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