Acta Neurochirurgica

, Volume 139, Issue 4, pp 349–354 | Cite as

Progesterone receptors in arachnoid cysts

An immunocytochemical study in 2 cases
  • K. G. Go
  • M. A. Blankenstein
  • T. M. Vroom
  • E. H. Blaauw
  • F. Dijk
  • H. Hollema
  • A. Verhagen
Clinical Articles


We report 2 cases of arachnoid cysts, one with a retrocerebellar and the other with a left temporal localization, in which immunohistochemical studies had been conducted. The results of the immunohistochemistry on the presence of carcino-embryonic antigen (CEA) and glial fibrillary acidic protein (GFAP), and of the scanning- and transmission electron microscopy revealed the cyst lining to be identical to subdural neurothelium. Progesterone receptors were found in the nuclei of cells lining the cyst, which also suggests the similarity of the cyst lining to arachnoid granulations and meningiomas as derivatives of subdural neurothelium, which also possess progesterone receptors.


Arachnoid (cyst, granulation) meningioma progesterone receptors 


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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • K. G. Go
    • 1
  • M. A. Blankenstein
    • 4
  • T. M. Vroom
    • 5
  • E. H. Blaauw
    • 2
  • F. Dijk
    • 2
  • H. Hollema
    • 3
  • A. Verhagen
    • 6
  1. 1.Department of NeurosurgeryUniversity and the University Hospital of GroningenThe Netherlands
  2. 2.Department of Medical Electron MicroscopyUniversity and the University Hospital of GroningenThe Netherlands
  3. 3.Department of PathologyUniversity and the University Hospital of GroningenThe Netherlands
  4. 4.Department of Endocrinology of the University Hospital of UtrechtThe Netherlands
  5. 5.Department of Pathology of the University Hospital of UtrechtThe Netherlands
  6. 6.Pharma Bioresearch ConsultancyThe Netherlands

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