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A statistical examination of self-ordering of amino acids in proteins

  • Randall A. Kok
  • John A. Taylor
  • Walter L. Bradley
Article

Abstract

Steinman and Cole (1967) have claimed that amino acids will naturally assume a nonrandom sequence when polymerized into polypeptides. They based their claim on a comparison of the frequency with which various dipeptide bonds formed in a dilute solution of amino acids to the various depeptide frequencies actually observed in ten proteins. Although the trends in the normalized frequencies go in the same direction, a statistical examination of the two sets of frequencies indicates that there is no correlation at all between experimental dipeptide frequencies and actual depeptide frequencies based on the chi-square tests.

Keywords

Organic Chemistry Geochemistry Polypeptide Dipeptide Nonrandom Sequence 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© D. Reidel Publishing Company 1988

Authors and Affiliations

  • Randall A. Kok
    • 1
  • John A. Taylor
    • 1
  • Walter L. Bradley
    • 2
  1. 1.Dept. of ChemistryMillikin UniversityDecaturUSA
  2. 2.Dept. of Mechanical EngineeringTexas A&M UniversityCollege StationUSA

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