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Phosphorylation of glyceric acid in aqueous solution using trimetaphosphate

  • Vera Kolb
  • Leslie E. Orgel
Article

Abstract

The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5 M trimetaphosphate in alkaline solution gives a mixture of 2- and 3-phosphoglyceric acids in combined yields of up to 40%.

Keywords

Phosphate Aqueous Solution Carbohydrate Organic Chemistry Geochemistry 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

P3!

trimetaphosphate

2-P

2-Phosphoglycerate

3-P

3-Phosphoglycerate

TSPS

3-trimethylsilyl propionic acid, sodium salt

NMR

nuclear magnetic resonance

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Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • Vera Kolb
    • 1
  • Leslie E. Orgel
    • 1
  1. 1.The Salk Institute for Biological StudiesSan DiegoUSA

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