The International Journal of Cardiac Imaging

, Volume 12, Issue 3, pp 191–195 | Cite as

Quantitative Doppler tissue imaging as a correlate of left ventricular contractility

  • David S. Bach


Doppler tissue imaging is a new noninvasive imaging modality that allows quantitation of the low intensity, high amplitude Doppler shifts in the range of myocardial tissue motion. This study was performed to test the hypothesis that Doppler tissue imaging may provide unique information reflecting left ventricular systolic function, and to test the relationship between myocardial tissue velocity and noninvasive measures of ventricular contractility. Nine patients with mild or moderate mitral insufficiency and no regional wall motion abnormality were studied during dobutamine stress echocardiography. Left ventricular ejection fraction and peak systolic velocity of the sub- endocardial left ventricular posterior wall were quantified at baseline and at peak stress and compared with estimated peak dP/dt. During dobutamine infusion, ejection fraction increased from 41.7±22.2 (range 14 to 70) % to 56.6±27.9 (range 17 to 84) % (p=0.001), peak systolic velocity increased from 22.7±4.2 (range 18 to 28) mm/sec to 35.3±10.1 (range 20 to 47) mm/sec (p=0.004), and dP/dt increased from 1050±322 (range 613 to 1574) mm Hg/sec to 1766±768 (range 936 to 3000) mm Hg/sec (p=0.01). Although there were good correlations between left ventricular dP/dt and both ejection fraction (R=0.75) and peak systolic velocity (R=0.81), the correlation between change in dP/dt and change in myocardial velocity (R=0.75) was better than that between change in dP/dt and change in ejection fraction (R=0.36). These data support the hypothesis that myocardial velocity determined with Doppler tissue imaging reflects myocardial contractility, and that catecholamine- induced alteration in contractility is better reflected by changes in myocardial velocity than by changes in ejection fraction.

Key words

echocardiography/Doppler left ventricular function myocardial contractility 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    McDicken WN, Sutherland GR, Moran CM, Gordon LN. Colour Doppler velocity imaging of the myocardium. Ultrasound in Med. & Biol. 1992; 18: 651–654.Google Scholar
  2. 2.
    Sutherland GR, Stewart MJ, Groundstroem KWE, Moran CM, Fleming A, Guell-Peris FJ, et al. Color Doppler myocardial imaging: a new technique for the assessment of myocardial function. J Am Soc Echocardiogr 1994; 7: 441–58.PubMedGoogle Scholar
  3. 3.
    Miyatake K, Yamagishi M, Tanaka N, Uematsu M, Yamazaki N, Mine Yet al. New method for evaluating left ventricular wall motion by color-coded tissue Doppler imaging: in vitro and in vivo studies. J Am Coll Cardiol 1995; 25: 717–24.PubMedGoogle Scholar
  4. 4.
    Donovan CL, Armstrong WF, Bach DS. Quantitative Doppler tissue imaging of the left ventricular myocardium: validation in normal subjects. Am Heart J 1995; 130: 100–4.PubMedGoogle Scholar
  5. 5.
    Uematsu M, Miyatake K, Tanaka N, Matsuda H, Sano A, Yamazaki N, et al. Myocardial velocity gradient as a new indicator of regional left ventricular contraction: detection by a two-dimensional tissue Doppler imaging technique. J Am Coll Cardiol 1995; 26: 217–23.PubMedGoogle Scholar
  6. 6.
    Bach DS, Armstrong WF. Dobutamine stress echocardiography. Am J Cardiol 1992; 69(20): 90H-96H.PubMedGoogle Scholar
  7. 7.
    Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I, Silverman NH, Tajik AJ. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J Am Soc Echo 1989; 2: 358–67.PubMedGoogle Scholar
  8. 8.
    Bargiggia GS, Bertucci C, Recusani F, Raisaro A, de Servi S, Valdez-Cruz LM, et al. A new method for estimating left ventricular dP/dt by continuous wave Doppler-echocardiography. Circulation 1989; 80: 1287–92.PubMedGoogle Scholar
  9. 9.
    Chen C, Rodriguez L, Guerrero L, Marshall S, Levine RA, Weyman AE, et al. Noninvasive estimation of the instantaneous first derivative of left ventricular pressure using continuouswave Doppler echocardiography. Circulation 1991; 83: 2101–10.PubMedGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1996

Authors and Affiliations

  • David S. Bach
    • 1
  1. 1.Department of Internal MedicineDivision of Cardiology University of MichiganAnn ArborUSA

Personalised recommendations