International Journal of Biometeorology

, Volume 17, Issue 3, pp 267–275 | Cite as

Effect of negative air ions upon emotionality and brain serotonin levels in isolated rats

  • G. O. Gilbert


The effect of small negative air ions on the emotional behavior and brain serotonin content of isolated rats was studied. The results indicate that isolated subjects were more reactive to handling and had larger levels of serotonin than did isolated subjects undergoing continuous ion treatment. Group housed subjects were less reactive to handling than were either isolated subjects or isolated subjects intermittently exposed to ions. Thus ions were effective in reducing both emotionality and serotonin. Only continuous ion treatment was effective.


Serotonin Plant Physiology Environmental Medicine Serotonin Level Emotional Behavior 
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Die Wirkung kleiner negativer Luftionen auf das Verhalten und den Serotoningehalt des Gehirns wurde an isolierten Ratten untersucht. Isolierte Tiere reagierten im Verhalten auf Ergreifen mit der Hand stärker und der Serotoningehalt war höher als bei gleich isolierten Tieren, die zusätzlich intermittierend Luftionen ausgesetzt waren. Durch Luftionen konnte danach die Emotionalität und der Serotoninspiegel herabgesetzt werden.


On étudie ici les répercussions de petits ions négatifs de l'air sur le comportement et le taux de sérotonine du cerveau de rats isolés. Les bêtes isolées réagissent plus violemment lorsqu'on les saisit à la main et leur taux de sérotonine est plus élevé que chez des bêtes, isolées également, mais auxquelles on a donné à respirer par intermittence des ions négatifs. Par conséquent, l'adjonction d'ions à l'air respiré a permis d'abaisser aussi bien l'impressionnabilité que le taux de sérotonine.


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  1. BEXTON, W.H., HERON, W. and SCOTT, T.G. (1954): Effects of decreased variation in the sensory environment. Canad.J.Psychol., 8: 70–76.PubMedGoogle Scholar
  2. BIRD, R.B., STEWART, W.E. and LIGHTFOOT, E.N. (1960): Transport Phenomena. John Wiley & Sons, New York.Google Scholar
  3. DUFFEE, R.A. and KOONTZ, R.H. (1965): Behavioral effects of ionized air on rats. Psychophysiology, 1: 347–359.PubMedGoogle Scholar
  4. FREY, A.H. (1967): Modification of the conditioned emotional response by treatment with small negative air ions. J.comp.Physiol.Psychol., 63: 121–125.PubMedGoogle Scholar
  5. GARATTINI, S. and VALZELLI, L. (1965): Serotonin. Elsevier Publishing Co., Amsterdam.Google Scholar
  6. KORN, J.H. and MOYER, K.E. (1968): Behavioral effects of isolation in the rat: the role of sex and time of isolation. J.genet.Psychol., 113: 263–273.PubMedGoogle Scholar
  7. KRUEGER, A.P., ANDRIESE, P.C. and KOTAKA, S. (1966): The effects of inhaling nonionized or positively ionized air containing 2–4% CO2 on the blood levels of 5-hydroxytryptamine in mice. Int.J.Biometeor., 10: 17–28.Google Scholar
  8. KRUEGER, A.P., ANDRIESE, P.C. and KOTAKA, S. (1968): Small air ions: their effect on blood levels of serotonin in terms of modern physical theory. Int.J.Biometeor., 12: 225–239.Google Scholar
  9. KRUEGER, A.P. and KOTAKA, S. (1969): The effects of air ions on brain levels serotonin in mice. Int.J.Biometeor., 13: 25–38.Google Scholar
  10. MAICKEL, R.P., COX, R.H., SAILLANT, J. and MILLER, F.P. (1968): A method for the determination of serotonin and norepinephrine in discrete areas of rat brain. Int. J. Neuropharmacol., 7: 275–281.PubMedGoogle Scholar
  11. MALYSHEVA, I.N. (1964): Meteorological and physiological significance of atmospheric ionization. Vestnik.Akad.Med.Nauk.SSR., 19: 83–89. (Abstract)Google Scholar
  12. MOYER, K.E. and KORN, J.H. (1965): Behavioral effects of isolation in the rat. Psychon.Sci., 3: 503–504.Google Scholar
  13. ROBINSON, N. and DIRNFELD, F.S. (1963): The ionization state of the atmosphere as a function of the meteorological elements and of various sources of ions. Int.J.Biometeor., 6: 101–110.Google Scholar
  14. SCHAEFER, K.E. (1959): Experiences with submarine atmospheres. J.Aviat.Med., 30: 350–359.PubMedGoogle Scholar

Copyright information

© Swets & Zeitlinger B.V. 1973

Authors and Affiliations

  • G. O. Gilbert
    • 1
  1. 1.Department of PsychologyPacific Lutheran UniversityTacomaUSA

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