Journal of Molecular Evolution

, Volume 9, Issue 4, pp 343–347 | Cite as

Primitive haemoglobin

  • Brian Tiplady
  • Morris Goodman
Article

Summary

The sequences ofPetromyzon andAplysia globins are compared with the postulated vertebrate and mollusc-vertebrate ancestors to see if differences exist in the rates of evolution of different types of residue positions. Between the mollusc-vertebrate ancestor andAplysia globin there is no very striking pattern of changes except that the interior positions are relatively conserved. In the evolution ofPetromyzon haemoglobin, theα1β2 contact area is relatively conserved. The homopolymeric binding of lamprey Hb seems to be a primitive function.

Key words

Evolution Haemoglobin Cooperativity Lamprey Maximum parsimony 

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Brian Tiplady
    • 1
  • Morris Goodman
    • 2
  1. 1.Astra Clinical Research UnitEdingburghUnited Kingdom
  2. 2.Department of AnatomyWayne State UniversityDetroitUSA

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