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Journal of Muscle Research & Cell Motility

, Volume 11, Issue 4, pp 331–337 | Cite as

Mechanical properties of mammalian single smooth muscle cells I. A low cost large range microforce transducer

  • J. J. Glerum
  • R. Van Mastrigt
Papers

Summary

A transducer has been developed for measuring the minute forces generated during isometric contractions (1.0–10.0μN) of single smooth muscle cells from the pig urinary bladder and the human uterus. In addition to its high sensitivity, resolution and stability (100 mVμN−1, <0.1μN and <2.0μN h−1), the transducer features a very wide range (100–140μN) with good linearity, enabling measurement of contractions as well as passive force-length characteristics within one uninterrupted measurement session. Since the transducer features an independent and interchangeable force to displacement conversion system, different force ranges can be realized by inserting force conversion systems with different compliances.

Keywords

Mechanical Property Smooth Muscle Muscle Cell Smooth Muscle Cell Large Range 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Chapman and Hall Ltd 1990

Authors and Affiliations

  • J. J. Glerum
    • 1
  • R. Van Mastrigt
    • 1
  1. 1.Department of UrologyErasmus UniversityDR RotterdamThe Netherlands

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