Papicrelektrophoretische Untersuchungen von Muskelextrakten bei nutritiver Muskeldystrophie
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Zusammenfassung
Papierelektrophoretisch wurden Muskelextrakte von Ratten mit chronischer Vitamin E-Mangeldystrophie untersucht. Die Myogenfraktion schien erniedrigt.
Wegen der mangelhaften Trennbarkeit der Proteinfraktionen können wir die Einführung dieser Technik in die Klinik zur Differenzierung neuromuskulärer Erkrankungen nicht empfehlen.
Summary
The effect of vitamin E deficiency on skeletal muscle of rats have been studied with the paper electrophoresis. The applied method gave an electrophoresis pattern in which only three fractions could be detected. The myogen components seem to be decreased in the deficient state.
We believe clinically the paper electrophoresis of muscle extracts is not suitable for the distinction between different neuromuscular disorders.
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