The diagnosis and treatment of the medulloblastoma has made remarkable advances in the 60 years that this tumor has been known. The survival time has increased but the quality of survival leaves much to be desired, according to a survey of the literature and the limited experiences in this study. The psychologic sequelae are particularly striking. This study gives a survey of diagnostic and therapeutic possibilities at this moment and goes further into some problems which are met during this process. A multidisciplinary approach is necessary because of the multitude of problems which are encountered. The problematic factors in the treatment and the course of the disease justify taking the patients into a trial in order to evaluate the different forms of treatment.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Bongartz, E. B., M. Bamberg, H. E. Nau, et al.: Optimal therapy in medulloblastoma. Acta Neurochir. 50 (1979) 117–125
Chin, H. W., Y. Maruyana: Early response and longterm results in the radiotherapy of childhood medulloblastoma. J. Neuro-Oncol. 1 (1983) 53–59
Choux, M., G. Lena, J. Hassoun: Prognosis and longterm follow-up in patients with medulloblastoma. Clin. Neurosurg. 30 (1982) 246–277
Deutsch, M.: The impact of myelography on the treatment results for medulloblastoma. Int. J. Radiat. Oncol. Biol. Phys. 10 (1984) 999–1003
Epstein, F.: The cavitron ultrasonic aspirator in tumor surgery. Clin. Neurosurg. 31 (1983) 497–505
Fasano, G. F., G. F. Lombard, R. M. Ponzio: Preliminary experiences with the use of three lasers (CO2, Nd — Yag, Argon) in some posterior fossa tumors in childhood. Childs Brain 10 (1983) 26–38
Hart, M. N., K. M. Earle: Primitive neuroectodermal tumors of the brain in children. Cancer 32 (1973) 890–897
Hirsch, J. F., D. Renier, P. Czernichow et al.: Medulloblastoma in childhood, survival and functional results. Acta Neurochir. 48 (1979) 1–15
Hoffmann, H. J., E. B. Hendrick, R. P. Humphreys: Management of medulloblastoma in childhood. Clin. Neurosurg. 30 (1982) 226–245
Ingraham, F. D., D. D. Matson: Neurosurgery of infancy and childhood. Thomas, Springfield, Illinois 1954
Packer, R. J., L. N. Sutton, L. B. Rorke et al.: Prognostic importance of cellular differentiation in medulloblastoma of childhood. J. Neurosurg. 61 (1984) 286–301
Rorke, L. B.: The cerebellar medulloblastoma and its relationship to primitive neuroectodermal tumors. J. Neuropathol. Exp. Neurol. (1983) 1–15
Silverman, C. L., H. Palkes, B. Talent et al.: Late effects of radiotherapy on patients with cerebellar medulloblastoma. Cancer 54 (1984) 825–829
Simesen, K., J. Haase, E. L. Madsen: Knoglemetastaser fra cerebellart medulloblastom. Ugeskr. Leager 146 (1984) 1139–1140
Voûte, P. A., J. A. Rammeloo, F. C. de Waal et al.: Medulloblastoma. Chemotherapy with vincristine, methotrexate and prednisolone in a “sandwich” scheme (Abstract). 13th Meeting of the International Society of Pediatric Oncology (SIOP). Marseilles Sept. 1981
Walther, B., P. Gutjahr: Development after treatment of cerebellar medulloblastoma in childhood. Tumours of the central nervous system in infancy and childhood. pp. 389–398. Springer-Verlag, Berlin—Heidelberg—New York 1982
About this article
Cite this article
Broere, G. Management of medulloblastoma in children, a multidisciplinary problem. Neurosurg. Rev. 9, 39–42 (1986). https://doi.org/10.1007/BF01743052
- multidisciplinary treatment
- survival rate and quality of survival