Chromosoma

, Volume 99, Issue 1, pp 3–10 | Cite as

Distribution of non-telomeric sites of the (TTAGGG)n telomeric sequence in vertebrate chromosomes

  • Julianne Meyne
  • Robert J. Baker
  • Holly H. Hobart
  • T. C. Hsu
  • Oliver A. Ryder
  • Oscar G. Ward
  • John E. Wiley
  • Doris H. Wurster-Hill
  • Terry L. Yates
  • Robert K. Moyzis
Article

Abstract

The intrachromosomal distribution of non-telomeric sites of the (TTAGGG)n telomeric repeat was determined for 100 vertebrate species. The most common non-telomeric location of this sequence was in the pericentric regions of chromosomes. A variety of species showed relatively large amounts of this sequence present within regions of constitutive heterochromatin. We discuss possible relationships between the non-telomeric distribution of the (TTAGGG)n sequence and the process of karyotype evolution, during which these sites may provide potential new telomeres.

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Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Julianne Meyne
    • 1
  • Robert J. Baker
    • 2
  • Holly H. Hobart
    • 3
  • T. C. Hsu
    • 4
  • Oliver A. Ryder
    • 5
  • Oscar G. Ward
    • 3
  • John E. Wiley
    • 6
  • Doris H. Wurster-Hill
    • 7
  • Terry L. Yates
    • 8
  • Robert K. Moyzis
    • 1
  1. 1.Genetics GroupLos Alamos National LaboratoryLos AlamosUSA
  2. 2.Department of Biological SciencesTexas Tech UniversityLubbockUSA
  3. 3.Department of Ecology and Evolutionary BiologyUniversity of ArizonaTucsonUSA
  4. 4.Department of Cell BiologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA
  5. 5.Center for Reproduction of Endangered SpeciesThe Zoological Society of San DiegoSan DiegoUSA
  6. 6.Department of Pediatrics, School of MedicineEast Carolina UniversityGreenvilleUSA
  7. 7.Department of PathologyDartmouth Medical SchoolHanoverUSA
  8. 8.Department of BiologyUniversity of New MexicoAlbuquerqueUSA

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