The phyletic distribution of Sm antigen in eukaryotes has been investigated by means of immunochemical techniques. This nuclear antigen, which is an acidic glycoprotein of about 7S with DNA binding ability, is present in all organisms examined. Such evidence suggests a very slow evolutionary rate for at least the antigenic determinant(s) of the Sm antigen.
This is a preview of subscription content, log in to check access.
Buy single article
Instant access to the full article PDF.
Price includes VAT for USA
Subscribe to journal
Immediate online access to all issues from 2019. Subscription will auto renew annually.
This is the net price. Taxes to be calculated in checkout.
Champion AB, Soderberg KL, Wilson AC, Ambler RP (1975) J Mol Evol 5:291
Miyachi K, Fritzler MJ, Tan EM (1978) J Immunol 121:2228
Nakamura RM (1974) Immunopathology. Clinical Laboratory Concepts and Methods. Little, Brown & Co, Boston, p 247
Northway JD, Tan EM (1972) Clin Immunol Immunopathol 1:6
Prager EM, Brush AH, Nolan RA, Nakanishi M, Wilson AC (1974) J Mol Evol 3:243
Tan SM, Kunkel HG (1966) J Immunol 94:464
Tan EM, Lerner RA (1972) J Mol Biol 68:107
Tan EM, Peebles C (1976) In: Rose NR, Friedman H (eds) Manual of clinical Immunology. Amer Soc Microbiol, Washington DC, p 660
Wallace GW, Wilson AC (1972) J Mol Evol 2:72
White TJ, Idrahimi IM, Wilson AC (1978) Nature 274:92
Whittaker RH (1969) Science 163:150
About this article
Cite this article
Nicotra, R., Natali, P. & Ferracin, A. Unchanged antigenic properties of a nuclear non-histone protein during phylogenesis. J Mol Evol 17, 256–258 (1981). https://doi.org/10.1007/BF01732764
- Protein evolution
- Nuclear proteins