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Journal of Molecular Evolution

, Volume 6, Issue 3, pp 185–197 | Cite as

Prebiotic peptide-formation in the solid state

III. Condensation Reactions of Glycine in Solid State Mixtures Containing Inorganic Polyphosphates
  • H. Sawai
  • L. E. Orgel
Article

Summary

The reactions of glycine with inorganic polyphosphates in the solid state have been studied. The formation of peptides up to the decamer occurs at moderate temperatures (r.t.−100°C) in the presence of imidazole and magnesium chloride. If adenosine 5′-monophosphate is added to the reaction mixture, 2′(3′)-O-glycyl adenosine 5′-monophosphate is also obtained. These reactions could have occurred on the primitive earth.

Key words

Prebiotic Activation Peptides Inorganic Polyphosphates Trimetaphosphate Amino Acids 

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References

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Copyright information

© Springer-Verlag 1975

Authors and Affiliations

  • H. Sawai
    • 1
  • L. E. Orgel
    • 1
  1. 1.The Salk Institute for Biological StudiesSan DiegoUSA

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