Klinische Wochenschrift

, Volume 63, Issue 10, pp 475–477 | Cite as

Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma

  • B. Rohrmoser
  • D. K. Lüdecke
  • P. C. Scriba


Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica. Despite these findings, the diagnosis of pituitary was confirmed Cushing's syndrome by computerized tomography and a transphenoidal operation.

Key words

Corticotropin-releasing factor (CRF) Cushing's disease ACTH 



corticotropin releasing factor


Cushing's disease


Cushing's syndrome


computerized tomography


growth hormone


follicle-stimulating hormone


luteinizing hormone


luteinizing hormone releasing hormone


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Copyright information

© Springer-Verlag 1985

Authors and Affiliations

  • B. Rohrmoser
    • 1
  • D. K. Lüdecke
    • 2
  • P. C. Scriba
    • 1
  1. 1.Klinik für Innere Medizin Medizinische Hochschule LübeckGermany
  2. 2.Neurochirurgische Abteilung Universitätskrankenhaus HamburgGermany

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