Journal of Molecular Evolution

, Volume 13, Issue 4, pp 295–304

A new estimate of sequence divergence of mitochondrial DNA using restriction endonuclease mappings

  • Norman Kaplan
  • Charles H. Langley

DOI: 10.1007/BF01731370

Cite this article as:
Kaplan, N. & Langley, C.H. J Mol Evol (1979) 13: 295. doi:10.1007/BF01731370


A new estimate of the sequence divergence of mitochondrial DNA in related species using restriction enzyme maps is constructed. The estimate is derived assuming a simple Posisson-like model for the evolutionary process and is chosen to maximize an expression which is a reasonable approximation to the true likelihood of the restriction map data. Using this estimate, four sets of mitochondrial DNA data are analyzed and discussed.

Key words

Evolution Restriction endonuclease mappings and mitochondrial DNA 

Copyright information

© Springer-Verlag 1979

Authors and Affiliations

  • Norman Kaplan
    • 1
  • Charles H. Langley
    • 1
  1. 1.Biometry Branch and Laboratory of Animal GeneticsNational Institute of Environmental Health SciencesNorth CarolinaUSA

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