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A case of rhinoscleroma cured with ciprofloxacin

Heilung eines Falles von Rhinosklerom mit Ciprofloxacin

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Summary

The diagnosis of rhinoscleroma was confirmed in a 17-year-old female patient from Tehran, Iran, suffering from a roundish tumour of the nose. Prior treatment with streptomycin and tetracycline had been unsuccessful. A three-month course of high-dose oral ciprofloxacin (750 mg b. i. d.) led to prompt cessation of the growth of the granuloma which was removed later by plastic surgery. Although serology alone appeared to have little value for the specific diagnosis of rhinoscleroma, a significant increase of IgG antibodies during treatment with ciprofloxacin confirmed infection byKlebsiella rhinoscleromatis in this case.

Zusammenfassung

Bei einer 17jährigen Patientin aus Teheran/Iran, die sich wegen einer tumorösen Raumforderung der Nase vorstellte, wurde histologisch die Diagnose eines Rhinoskleroms gesichert. Da vorangegangene Behandlungen mit Streptomycin und Tetrazyklinen erfolglos geblieben waren, wurde ein Therapieversuch mit hochdosiertem Ciprofloxacin (2 × 750 mg/d p. o.) unternommen. Unter der Therapie kam es zu einem raschen Wachstumsstillstand des Granuloms, das später chirurgisch entfernt wurde. Serologische Untersuchungen zeigten einen signifikanten Anstieg von IgG-Antikörpern gegenKlebsiella rhinoscleromatis unter der Therapie. Die Patientin ist seit mehr als drei Jahren symptomlos.

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Trautmann, M., Held, T., Ruhnke, M. et al. A case of rhinoscleroma cured with ciprofloxacin. Infection 21, 403–406 (1993). https://doi.org/10.1007/BF01728925

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Keywords

  • Public Health
  • Internal Medicine
  • Infectious Disease
  • Streptomycin
  • General Practice