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Transferrin-reticulocyte cycle time in rat reticulocytes

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The uptake and release of131I-labelled diferric transferrin by rat reticulocytes was examined both in vitro and in vivo. Cycle time in vitro was estimated to be 2.5 min in iron-deficient reticulocytes and 2.3 min in phenylhydrazine-produced reticulocytes. In vivo reticulocyte uptake and release of labelled diferric transferrin injected in the iron-deficient rat averaged 1.7 min.

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Correspondence to Helmut A. Huebers.

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Intragumtornchai, T., Huebers, H.A. & Finch, C.A. Transferrin-reticulocyte cycle time in rat reticulocytes. Blut 60, 249–252 (1990). https://doi.org/10.1007/BF01728793

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Key words

  • Transferrin
  • Transferrin receptors
  • Reticulocyte iron uptake