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Intensive Care Medicine

, Volume 22, Issue 2, pp 116–121 | Cite as

Calcium free hemodialysis: Experience in the treatment of 33 patients with severe hypercalcemia

  • C. Camus
  • C. Charasse
  • I. Jouannic-Montier
  • P. Seguin
  • Y. L. Tulzo
  • J. Bouget
  • R. Thomas
Original

Abstract

Objective

To assess the efficacy, adverse effects and relevance of calcium-free hemodialysis (CFHD) in the treatment of major hypercalcemia.

Design

Retrospective chart review.

Setting

Medical ICU.

Patients

All patients admitted over a 9-year period for hypercalcemia requiring urgent treatment and who underwent hemodialysis.

Interventions

CFHD with an acetate dialysate.

Main results

Thirty-three patients with severe hypercalcemia from various etiologies received CFHD. Marked and rapid decrease of serum total calcium was obtained during all sessions (mean decrease: 1.71±0.54 mmol/l). Calcium rebound within 24 h after CFHD was observed in all evaluable cases (1±0.45 mmol/l; mean delay 13.7±5.8 h). Adverse cardiovascular effects occurred in 17 of 48 sessions (35%) and in 13 of 30 evaluable patients (43%).

Conclusions

Adverse effects are frequent during CFHD. After correction of hypovolemia, its use should be restricted to patients with severe clinical symptoms or advanced renal impairment.

Key words

Hypercalcemia Hemodialysis Calcium-free dialysate Acetate dialysate 

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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • C. Camus
    • 1
  • C. Charasse
    • 2
  • I. Jouannic-Montier
    • 1
  • P. Seguin
    • 1
  • Y. L. Tulzo
    • 1
  • J. Bouget
    • 3
  • R. Thomas
    • 1
  1. 1.Service de Réanimation MédicaleHôpital PontchaillouRennesFrance
  2. 2.Service de NéphrologieHôpital PontchaillouRennesFrance
  3. 3.Service des UrgencesHôpital PontchaillouRennesFrance

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