Intensive Care Medicine

, Volume 22, Issue 2, pp 116–121 | Cite as

Calcium free hemodialysis: Experience in the treatment of 33 patients with severe hypercalcemia

  • C. Camus
  • C. Charasse
  • I. Jouannic-Montier
  • P. Seguin
  • Y. L. Tulzo
  • J. Bouget
  • R. Thomas



To assess the efficacy, adverse effects and relevance of calcium-free hemodialysis (CFHD) in the treatment of major hypercalcemia.


Retrospective chart review.


Medical ICU.


All patients admitted over a 9-year period for hypercalcemia requiring urgent treatment and who underwent hemodialysis.


CFHD with an acetate dialysate.

Main results

Thirty-three patients with severe hypercalcemia from various etiologies received CFHD. Marked and rapid decrease of serum total calcium was obtained during all sessions (mean decrease: 1.71±0.54 mmol/l). Calcium rebound within 24 h after CFHD was observed in all evaluable cases (1±0.45 mmol/l; mean delay 13.7±5.8 h). Adverse cardiovascular effects occurred in 17 of 48 sessions (35%) and in 13 of 30 evaluable patients (43%).


Adverse effects are frequent during CFHD. After correction of hypovolemia, its use should be restricted to patients with severe clinical symptoms or advanced renal impairment.

Key words

Hypercalcemia Hemodialysis Calcium-free dialysate Acetate dialysate 


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Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • C. Camus
    • 1
  • C. Charasse
    • 2
  • I. Jouannic-Montier
    • 1
  • P. Seguin
    • 1
  • Y. L. Tulzo
    • 1
  • J. Bouget
    • 3
  • R. Thomas
    • 1
  1. 1.Service de Réanimation MédicaleHôpital PontchaillouRennesFrance
  2. 2.Service de NéphrologieHôpital PontchaillouRennesFrance
  3. 3.Service des UrgencesHôpital PontchaillouRennesFrance

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