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Diagnostics and categories of patients

Diagnostische Maßnahmen und Gruppeneinteilung von Patienten

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Care in identifying and categorizing patients is a critical first step in proper drug evaluation. The appropriate diagnostic tests include culture and urinalysis. They are essential for the firm establishment of a diagnosis and should be sensitive and specific enough to meet the appropriate clinical requirements. The clinical categories outlined are encountered in clinical practice with a frequency that is sufficient to provide enough patients for an assessment of the response to antimicrobial therapy and to give information that will have practical value for clinicians.


Bei der Beurteilung eines Medikamentes ist es wichtig, daß die Patienten genau beschrieben und in Gruppen eingeteilt werden. Zu den wichtigsten diagnostischen Maßnahmen gehören die Urinkultur und die Urinanalyse. Diese Maßnahmen sind notwendig um eine genaue Diagnose zu stellen und sie sollten in der entsprechenden klinischen Situation auch ausreichend sensitiv und spezifisch sein. Die klinischen Gruppen, die vorgeschlagen werden, sollten in der klinischen Praxis groß genug sein, damit genügend Patienten dazu eingeteilt werden können. Nur so kann die therapeutische Wirksamkeit eines Antibiotikums bestimmt werden, wenn das Ergebnis für den Kliniker relevant sein soll.

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  1. 1.

    Sobel, J. D., Kay, D. Urinary tract infections. In:Mendell, G. L., Douglas, R. G. Jr., Bennett, J. E. (eds.): Principles and practice of infectious diseases. Third edition. Churchill Livingstone, New York 1990, pp. 582–611.

  2. 2.

    Johnson, J. R., Stamm, W. E. Diagnosis and treatment of acute urinary tract infections. Inf. Clin. North Am. 1 (1987) 773–797.

  3. 3.

    Bollgren, I., Engstrom, C. F., Hammarlind, M., Kallenius, G., Riengertz, H., Svenson, S. B. Low urinary counts of P-fimbriatedEscherichia coli in presumed acute pyelonephritis. Arch. Dis. Child. 59 (1984) 102–106.

  4. 4.

    Stamm, W. E., Counts, G. W., Running, K. R., Fihn, S., Turck, M., Holmes, K. K. Diagnosis of coliform infection in acutely dysuric women. N. Engl. J. Med. 307 (1982) 463–468.

  5. 5.

    Stamm, W. E. Measurement of pyuria and its relation to bacteriuria. Am. J. Med. 75 (1983) 53.

  6. 6.

    Ronald, A. R. Current concepts in the management of urinary tract infections in adults. Med. Clin. North Am. 68 (1984) 335–349.

  7. 7.

    Komaroff, A. L. Urinalysis and urine culture in women with dysuria. Ann. Intern. Med. 104 (1986) 212–218.

  8. 8.

    Fairley, K. F., Carson, N. E., Gutch, R. C., Leighton, P., Grounds, A. D., Laird, E. C., McCallum, P. H., Sleeman, R. L., O'Keefe, C. M. Site of infection in acute urinary-tract infection in general practice. Lancet ii (1971) 615–618.

  9. 9.

    Jones, S. R., Smith, S. W., Sanford, J. P. Localization of urinary-tract infections by detection of antibody-coated bacteria in urine sediment. N. Engl. J. Med. 290 (1974) 591–593.

  10. 10.

    Rubin, R. H., Fang, L. S., Jones, S. R., Munford, R. S., Slepack, J. M., Varga, P. A., Onheiber, L., Hall, C. L., Tolkoff-Rubin, N. E. Single-dose amoxicillin therapy for urinary tract infection: Multicenter trial using antibody-coated bacteria localization technique. JAMA 244 (1980) 561–564.

  11. 11.

    Bahnson, R. R. Urosepsis. Urol. Clin. North Am. 13 (1986) 625–635.

  12. 12.

    Anderson, R. U. Urinary tract infections in compromised hosts. Urol. Clin. North Am. 13 (1986) 727–734.

  13. 13.

    Cattell, W. R. Urinary tract infections in adults. Postgrad. Med. J. 61 (1985) 907–913.

  14. 14.

    Preheim, L. C. Complicated urinary tract infections. Am. J. Med. 79 (1985) 62–66.

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Schaeffer, A.J. Diagnostics and categories of patients. Infection 20, S138–S142 (1992). https://doi.org/10.1007/BF01704354

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  • Internal Medicine
  • Clinical Practice
  • Infectious Disease
  • General Practice
  • Diagnostic Test