Prevalence of primaryHelicobacter pylori resistance to metronidazole and clarithromycin in The Netherlands

  • A. A. van Zwet
  • W. A. de Boer
  • P. M. Schneeberger
  • J. Weel
  • A. R. Jansz
  • J. C. Thijs
Notes

DOI: 10.1007/BF01691216

Cite this article as:
van Zwet, A.A., de Boer, W.A., Schneeberger, P.M. et al. Eur. J. Clin. Microbiol. Infect. Dis. (1996) 15: 861. doi:10.1007/BF01691216

Abstract

The minimum inhibitory concentrations of metronidazole and clarithromycin were determined for 780Helicobacter pylori strains collected in 1994 and 1995 from three different regions in The Netherlands. The overall prevalence of primary metronidazole resistance was 17%, with resistance found more frequently in women (24%) than in men (13%). There was no significant difference between the levels of resistance in the three regions. Primary clarithromycin resistance was rare (1%) and relatively infrequent as compared to that found in other countries. Four of the six strains resistant to clarithromycin were also resistant to metronidazole.

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • A. A. van Zwet
    • 1
  • W. A. de Boer
    • 2
  • P. M. Schneeberger
    • 3
  • J. Weel
    • 4
  • A. R. Jansz
    • 5
  • J. C. Thijs
    • 6
  1. 1.Regional Public Health Laboratory Groningen/DrentheBethesda HospitalAA HoogeveenThe Netherlands
  2. 2.Department of Internal MedicineSint Anna ZiekenhuisBE OssThe Netherlands
  3. 3.Laboratory for Medical MicrobiologyBosch MedicentrumNL Den BoschThe Netherlands
  4. 4.Department of Medical MicrobiologyAcademic Medical CentreAZ AmsterdamThe Netherlands
  5. 5.Laboratory for Medical Microbiology PAMMAA VeldhovenThe Netherlands
  6. 6.Department of Internal MedicineBethesda HospitalAA HoogeveenThe Netherlands

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