The identification of five unreported lindane metabolites recovered from rat urine

  • R. W. Chadwick
  • J. J. Freal
Article

Summary

Previously unreported metabolites from the urine of rats fed lindane have been identified as 3,4-dichlorophenol, 2,4,6-trichlorophenol, 2,3,4,5-tetrachlorophenol, 2,3,4,6-tetrachlorophenol and 2,3,4,5,6-pentachloro-2-cyclohexen-1-ol. While the 3,4-dichlorophenol is a minor metabolite, the others are excreted in greater quantities than either 2,3,5- or 2,4,5-trichlorophenol, previously identified lindane metabolites. The excretion of tetrachlorophenols and PCCOL require a revision in the currently accepted theory regarding the metabolism of lindane by mammals.

Keywords

Waste Water Water Management Water Pollution Lindane Minor Metabolite 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag New York Inc. 1972

Authors and Affiliations

  • R. W. Chadwick
    • 1
  • J. J. Freal
    • 1
  1. 1.Perrine Primate LaboratoryEnvironmental Protection AgencyPerrine

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