The Histochemical Journal

, Volume 18, Issue 8, pp 413–420 | Cite as

Immunogold localization of ingested kidney bean (Phaseolus vulgaris) lectins in epithelial cells of the rat small intestine

  • T. P. King
  • A. Pusztai
  • G. Grant
  • D. Slater
Papers
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Summary

The interactions between dietary kidney bean (Phaseolus vulgaris) lectins and the epithelial cells of the rat small intestine were investigated by immunogold electron microscopy. The results demonstrated that the lectins bind to the glycocalyx of duodenal and jejunal microvilli and that some of these dietary constituents are endocytosed into lysosomal pathways within both absorptive and secretory gut cells. It is concluded that the lysosomal response serves to limit the absorption of nutritionally significant levels of these dietary toxins.

Keywords

Electron Microscopy Epithelial Cell Small Intestine Kidney Bean Dietary Constituent 
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Copyright information

© Chapman and Hall Ltd. 1986

Authors and Affiliations

  • T. P. King
    • 1
  • A. Pusztai
    • 1
  • G. Grant
    • 1
  • D. Slater
    • 1
  1. 1.Rowett Research Institute, BucksburnAberdeenScotland

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