World Journal of Surgery

, Volume 6, Issue 1, pp 61–65 | Cite as

Metastatic disease in the liver from colorectal cancer: An appraisal of liver surgery

  • Stig Bengmark
  • Larsolof Hafström
  • Bengt Jeppsson
  • Per-Ebbe Jönsson
  • Stefan Rydén
  • Kaj Sundqvist


This study supports the opinion that liver resection or metastasis enucleation with a margin of normal tissue around the tumor for liver metastases from colorectal cancer can be recommended. The 3-year survival rate of 20–25% is far better than the 3-year survival rates reported after resection of the primary organ for cancers such as, for example, the pancreas and esophagus and is almost as good as that of surgery of primary rectal cancer Dukes' C. Liver resection has an acceptably low postoperative mortality (less than 10%), morbidity, and complication rate.


Colorectal Cancer Normal Tissue Rectal Cancer Complication Rate Liver Metastasis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Cette étude permet d'affirmer que les méthodes de résection hépatique ou d'énucléation résection appliquées aux metastases hépatiques des cancers coliques et rectaux méritent d'Être tentées. Le taux de survie à 3 ans est de 20 à 25 pour cent. Il est supérieur à celui des exérèses pour cancer de l'oesophage ou par cancer du pancréas par exemple. Il est presqu'aussi satisfaisant que le taux de survie après exérèse du cancer rectal ayant atteint le type C de la classification de Dukes.

La résection hépatique a un taux de complication, de morbidité et de mortalité post opératoire bas acceptable (moins de 10%).


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Grinnell, R.S.: Results in the treatment of carcinoma of the colon and rectum. An analysis of 2341 cases over a 35-year period with 5-year survival. Results in 667 patients. Surg. Gynecol. Obstet.96:31, 1953Google Scholar
  2. 2.
    Berge, T., Ekelund, T., Mellner, G., Pihl, C., Wenckert, A.: Carcinoma of the colon-rectum in a defined population. Acta Chir. Scand. (Suppl.): 1, 1973Google Scholar
  3. 3.
    Bengmark, S., Hafström, L.: The natural history of primary and secondary malignant tumors of the liver. I. The prognosis for patients with hepatic metastases from colonic and rectal carcinoma verified by laparotomy. Cancer23:198, 1969Google Scholar
  4. 4.
    Bengmark, S., Hafström, L.: The natural course for liver malignancy. Prog. Clin. Cancer7:195, 1978Google Scholar
  5. 5.
    Oxley, E.M., Ellis, H.: Prognosis of carcinoma of the large bowel in the presence of liver metastases. Br. J. Surg.56:149, 1969Google Scholar
  6. 6.
    Baden, H., Andersen, B.: Survival of patients with untreated liver metastases from colorectal cancer. Scand. J. Gastroenterol.10:221, 1975Google Scholar
  7. 7.
    Foster, J.H.: Survival after liver resection for secondary tumors. Am. J. Surg.135:389, 1978Google Scholar
  8. 8.
    Wilson, S.M., Adson, M.D.: Surgical treatment of hepatic metastases from colorectal cancer. Arch. Surg.111:330, 1976Google Scholar
  9. 9.
    Wanebo, H.J., Semoglou, C., Attiyeh, F., Stearns, M.J., Jr.: Surgical management of patients with primary operable colorectal cancer and synchronous liver metastases. Am. J. Surg.135:81, 1978Google Scholar
  10. 10.
    Fortner, J.G., Kim, D.K., MacLean, B.J., Barrett, N.M.K., Iwatsuki, S., Turnbull, A.D., Howland, W.S., Beattie, E.J.: Major hepatic resection for neoplasm-personal experience in 108 patients. Ann. Surg.188:361, 1978Google Scholar
  11. 11.
    Tung, T.T., Quang, N.G.: A new technique for operating on the liver. Lancet1:192, 1963Google Scholar
  12. 12.
    Wood, G.B., Gilles, L.R., Blumgart, L.H.: A retrospective study of the natural history of patients with liver metastases from colorectal cancer. Clin. Oncol.2:285, 1976Google Scholar
  13. 13.
    Nielsen, J., Balslev, J., Jensen, H.E.: Carcinoma of the colon with liver metastases. Acta Chir. Scand.137:463, 1971Google Scholar
  14. 14.
    Almersjö, O., Bengmark, S., Hafström, L.: Liver resection for cancer. Acta Chir. Scand.142:139, 1976Google Scholar
  15. 15.
    Dupont, J.B., Jr., Lee, J.R., Burton, G.R., Cohn, I.: Adenocarcinoma of the stomach: Review of 1497 cases. Cancer41:941, 1978Google Scholar
  16. 16.
    McNeer, G., Bowden, L., Booher, R.J., McPeak, C.J.: Elective total gastrectomy for cancer of the stomach: End results. Ann. Surg.180:252, 1974Google Scholar
  17. 17.
    Warren, K.W., Cattell, R.B., Blackburn, J.P., Nora, P.F.: A long-term appraisal of pancreaticoduodenal resection for periampullary carcinoma. Ann. Surg.155:653, 1962Google Scholar
  18. 18.
    Brooks, J.R., Calebras, J.M.: Cancer of the pancreas. Palliative operation, Whipple procedure or total pancreatectomy? Am. J. Surg.131:516, 1976Google Scholar
  19. 19.
    Ihse, I., Lilja, P., Arnesjö, B., Bengmark, S.: Total pancreatectomy for cancer—an appraisal of 65 cases. Ann. Surg.186:674, 1977Google Scholar
  20. 20.
    Cady, B., Bonneval, M., Fender, H.: Elective hepatic resection. Am. J. Surg.137:514, 1979Google Scholar
  21. 21.
    Attiyeh, F.F., Wanebo, H.J., Stearns, M.W., Jr.: Hepatic resection for metastases from colorectal cancer. Dis. Colon Rectum21:160, 1978Google Scholar
  22. 22.
    Parker, E.F., Gregorie, H.B.: Carcinoma of the esophagus: Long-term results. J.A.M.A.235:1018, 1976Google Scholar
  23. 23.
    Taylor, I.: Cytotoxic perfusion for colorectal liver metastases. Br. J. Surg.65:109, 1978Google Scholar
  24. 24.
    Taylor, I., Rowling, J., West, C.: Adjuvant cytotoxic liver perfusion for colorectal cancer. Br. J. Surg.66:833, 1979Google Scholar
  25. 25.
    Starzl, T.E., Putnam, C.W.: Surgical approaches to primary and metastatic liver neoplasms. Int. J. Radiat. Oncol. Biol. Phys.1:959, 1976Google Scholar

Copyright information

© Société Internationale de Chirurgie 1982

Authors and Affiliations

  • Stig Bengmark
    • 1
  • Larsolof Hafström
    • 1
  • Bengt Jeppsson
    • 1
  • Per-Ebbe Jönsson
    • 1
  • Stefan Rydén
    • 1
  • Kaj Sundqvist
    • 1
  1. 1.Department of SurgeryUniversity of LundLundSweden

Personalised recommendations