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Carotid body tumors at high altitudes: Quito, Ecuador, 1987

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Abstract

Carotid body tumors seem to be encountered more frequently in people living at high altitudes. Twenty lesions operated in 19 patients at a general hospital in Quito, Ecuador over a period of only 5 years are reported. All patients lived in the highlands of the Andean region. There was no operative mortality, and morbidity was comparable to other series. No malignant cases were found. A higher degree of suspicion to recognize tumors and to operate at an earlier stage of development and thereby diminish operative morbidity is recommended. The great reliability of contrast angiogram and the development of other noninvasive diagnostic techniques is stressed. A study of the incidence of this lesion in the entire country should be made in the future.

Résumé

Les tumeurs du glomus carotidien (GC) semblent plus fréquentes en haute altitude. Vingt tumeurs du GC ont été opérées chez 19 patients dans une période de 5 ans dans un hopital général à Quito. Tous les patients habitaient les hauts plateaux des Andes. Il n'y avait pas de mortalité; la morbidité était similaire aux autres séries. Il n'y avait pas de tumeur maligne. Il faut penser à cette lésion plus souvent pour en faire le diagnostic et l'opérer plus tôt, réduisant ainsi la morbidité opératoire. L'angiographie et d'autres méthodes non invasives sont fiables. Des auteurs suggèrent d'entreprendre une étude de l'incidence de cette affection pour le pays dans son ensemble.

Resumen

Los tumores del cuerpo carotídeo parecen ocurrir con mayor frecuencia en personas que residen a grandes altitudes. Se informan 20 iesiones operadas en 19 pacientes en un hospital general de Quito, Ecuador en un período de apenas 5 años. La totalidad de los pacientes residía en zonas altas de la región andina. No hubo mortalidad operatoria, y la morbilidad fue comparable a la informada en otras series. No encontramos casos de malignidad. Se debe mantener un alto índice de sospecha frente a pacientes con masas cervicales laterales, con el objeto de que estos tumores puedan ser reconocidos y operados en fases tempranas de su desarrollo a fin de disminuír la morbilidad y mortalidad. Se enfatiza la gran confiabilidad de la angiografía de contraste y el desarrollo de otras técnicas no invasivas de diagnóstico. Creemos que en el futuro debe realizarse un estudio sobre la incidencia de esta lesión en el territorio nacional.

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References

  1. 1.

    Bosq, J., Caillaud, J., Micheau, C., Luboinski, B., Marandas, P., Richard, J.M.: Etude anatomo-pathologique des paragangliomes cervico-cephaliques. Actualités de carcinologie cervico-faciale, vol. 10, Paris, Masson, 1984, p. 17

  2. 2.

    Farr, H.W.: Carotid body tumors: A 40-year study. Cancer30:260, 1980

  3. 3.

    Saldana, M.J., Salem, L.E., Travezan, R.: High altitude hypoxia and chemodectomas. Hum. Pathol.4:251, 1974

  4. 4.

    Krause-Senties, L.: Tumores del cuerpo carotideo. Arch. Invest. Med.2:25, 1977

  5. 5.

    Loré, J.M.: An Atlas of Head and Neck Surgery, Philadelphia, W.B. Saunders Co., 1973, p. 891

  6. 6.

    Parry, D.M., Li, F.P., Strong, L.O., Carney, J.A., Schottenfeld, D., Reimer, R.R., Grufferman, S.: Carotid body tumors in humans. J. Natl. Cancer Inst.68:573, 1982

  7. 7.

    Grufferman, S., Gillman, M.W., Pasternak, L.R., Peterson, C.L., Young, W.G.: Familial carotid body tumors: Case report and epidemiologic review. Cancer46:2116, 1980

  8. 8.

    Coia, L.R., Fazekas, J., Farb, S.N.: Familial chemodectoma. Int. J. Rad. Oncol. Biol. Phys.7:949, 1981

  9. 9.

    Leeds, C.D., Levine, H.L., Beven, E.G., Tucker, H.M.: Tumors of the carotid body, experience with 41 cases. Am. J. Surg.142:362, 1981

  10. 10.

    Rosen, I.B., Palmer, J.A., Goldberg, M., Mustard, R.A.: Vascular problems associated with carotid body tumors. Am. J. Surg.142:439, 1981

  11. 11.

    You-xian, F., Qun, S.: Surgical treatment of carotid body tumors. Chin. Med. J.95:417, 1982

  12. 12.

    Dent, T.L., Thompson, N.W., Fry, W.J.: Carotid body tumors. Surgery80:365, 1976

  13. 13.

    Laird, J.D., Ferguson, W.R., Moilpath, E.M., Hamilton, J.R.: Radionuclide angiography as the primary investigation in chemodectoma: Concise communication. J. Nucl. Med.24:475, 1983

  14. 14.

    Shuber, M.A., Mafee, M.F.: Diagnosis of carotid body tumors by dynamic computerized tomography. Head Neck Surg.4:518, 1982

  15. 15.

    Mafee, M.F.: Dynamic CT and its application to otolaryngology—Head and neck surgery. J. Otolaryngol.11:307, 1982

  16. 16.

    Mäkäräinen, H., Päivänsalo, M., Hyrykangas, K., Leinonen, A., Siniluoto, T.: Sonographic patterns of carotid body tumors. J. Clin. Ultrasound14:373, 1986

  17. 17.

    Olsen, W.L., Dillon, W.P., Kelly, W.M., Norman, D., Zawaski, M.B., Newton, T.H.: MR imaging of paragangliomas. Am. J. Roentgenol.148:201, 1987

  18. 18.

    Padberg, F.T., Gady, B., Persson, A.V.: Carotid body tumor, the Lahey Clinic experience. Am. J. Surg.145:526, 1983

  19. 19.

    Natali, J.: Les chémodectomas latéro-cervicaux. Actualités de carcinologie cervico-faciale, vol. 10, Paris, Masson, 1984, p. 53

  20. 20.

    Chabolle, F., Laccourreye, O., Meyer, B., Brasnu, D., Laccourreye, H., Chouard, C.H.: Interêts et limites de l'embolisation dans les paraganglimas cervicaux, à propos de 20 cas. Ann. Oto-Laryng. (Paris)104:243, 1987

  21. 21.

    Kendall, B.: Paragangliomas: Treatment by embolization. In Head and Neck Oncology, New York, Raven Press, 1986, p. 195

  22. 22.

    Fobt, K.: Zur technik der operativen behandlung der glomus caroticum-tumoren. Laryngol. Rhino. Otol.60:57, 1981

  23. 23.

    Farr, H.W.: Carotid body tumors: A thirty year experience at Memorial Hospital. Am. J. Surg.114:614, 1967

  24. 24.

    Irons, G.B., Weiland, L.H., Brown, W.L.: Paragangliomas of the neck, clinical and pathological analysis of 116 cases. Surg. Clin. North Am.57:575, 1977

  25. 25.

    Van Asperen, B.P., Terpstra, J.L., Vink, M.: Diagnosis, treatment and operative complications of carotid body tumors. Br. J. Surg.68:433, 1981

  26. 26.

    Zikk, D., Shanon, E., Papoport, Y., Samuel, J.: Sleep apnea following bilateral excision of carotid body tumors. Laryngoscope93:1470, 1983

  27. 27.

    Meyer, F.B., Sundt, T.M., Pearson, B.W.: Carotid body tumors: A subject review and suggested surgical approach. J. Neurosurg.64:377, 1986

  28. 28.

    Merino, M.J., Livolsi, V.A.: Malignant carotid body tumors: Report of two cases and review of the literature. Cancer47:1403, 1981

  29. 29.

    Dial, P., Marks, C., Bolton, J.: Current management of paragangliomas. Surg. Gynecol. Obstet.155:187, 1982

  30. 30.

    Krupski, W.C., Effeney, D.J., Ehrenfeld, W.K., Stoney, R.J.: Cervical chemodectoma, technical considerations and management options. Am. J. Surg.144:215, 1982

  31. 31.

    Sykes, J.M., Ossoff, R.H.: Paragangliomas of the head and neck. Otolaryngol. Clin. North Am.19:755, 1986

  32. 32.

    Dickinson, P.H., Griffin, S.M., Guy, A.J., McNeill, I.F.: Carotid body tumor: 30 year experience. Br. J. Surg.73:14, 1986

  33. 33.

    Zanaret, M., Thomassin, J.M., Scavennec, C., Cannoni, M., Pech, A.: Les chémodectomes latéro-cervicaux. Actualités de carcinologie cervico-faciale, vol. 10, Paris, Masson, 1984, p. 64

  34. 34.

    Marandas, P., Lepajolec, C., Bosq, J., Schwaab, G., Piekarski, D., Lengrand, D., Wibault, P., Richard, J.M.: Etude clinique des paragangliomes cervico-cephaliques suivis à l'Institut Gustave Roussy. Actualités de carcinologie cervico-faciale, vol. 10, Paris, Masson, 1984, p. 27

  35. 35.

    Gaillard, J., Haguenauer, J.P., Pignat, J.C., Levai, J., Dubreuil, C.: Les chémodectomes du corpuscule carotidien. Actualités de carcinologie cervico-faciale, vol. 10, Paris, Masson, 1984, p. 75

  36. 36.

    Rodriguez-Cuevas, H., Lau, I., Rodriguez, H.P.: High altitude paragangiiomas, diagnostic and therapeutic considerations. Cancer57:672, 1986

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Correspondence to Luis Pacheco-Ojeda M.D..

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Pacheco-Ojeda, L., Durango, E., Rodriquez, C. et al. Carotid body tumors at high altitudes: Quito, Ecuador, 1987. World J. Surg. 12, 856–859 (1988). https://doi.org/10.1007/BF01655498

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Keywords

  • Cardiac Surgery
  • General Hospital
  • Vascular Surgery
  • Thoracic Surgery
  • High Altitude