Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Primary malignant pericardial mesothelioma

  • 23 Accesses

  • 2 Citations


Malignant primary tumors of the pericardium are rare. The autors present two male patients, aged 44 and 67 years, not exposed to asbestos, who died from pericardial mesothelioma. Repeated evacuation of fluid from the pericardium due to cardiac tamponade failed to reveal the cause of pericarditis. In one case, the diagnosis was made on surgical exploration, and in the other, at autopsy. A significant difference between benign and malignant pericardial effusion was observed. In cases of pericardial mesothelioma, symptoms of epicardial involvement cannot be attributed solely to the hindered inflow and cardiac tamponade, but also to congestive heart failure due to myocardial infiltration. In one patient, temporary improvement was achieved, first by pronisone therapy and then by radiotherapy.

This is a preview of subscription content, log in to check access.


  1. 1.

    Antman K, Blum R, Greenberger I et al. (1980) Multimodality therapy for malignant mesothelioma based on a study of natural history. Am J Med 3:356–620

  2. 2.

    Antman KH (1981) Clinical presentation and natural history of benign and malignant mesothelioma. Semin Oncol 3:313–320

  3. 3.

    Cancer register, 1976–1986. Ljubljana; Okološki inštitut

  4. 4.

    Chahinian AP, Holland JF (1981) Treatment of diffuse malignant mesothelioma: a review. Mt Sinai J Med (NY) 50:54–67

  5. 5.

    Kaden F (1982) Metastasierendes Perikardmesotheliom. Z Kardiol 71:485–487

  6. 6.

    Llewellyn MJ, Wotkinson M, Fabri B (1987) Pericardial constriction caused by primary mesothelioma. Br Heart J 57:54–57

  7. 7.

    Mirabella F (1982) Contributo all'epidemiologia del mesothelioma pericardico. Ita-pathologica 1030:251–229

  8. 8.

    Stanulla H, Runkewitz V (1983) Primare Tumoren des Herzens und Herzbeutels. Zentralbl Allg Pathol 127:125–133

  9. 9.

    Vita TV, Hellman S, Rosenberg SA (1981) Cancer. Principles and practice of oncology. Lippincott, Philadelphia, pp 1571–1581

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Turk, J., Kenda, M. & Kranjec, I. Primary malignant pericardial mesothelioma. Klin Wochenschr 69, 674–678 (1991). https://doi.org/10.1007/BF01649430

Download citation

Key words

  • Pericardial Mesothelioma
  • Epidemiology
  • Diagnosis