New approaches in the treatment of the dystonias
Review
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Summary
At this point the treatment of dystonias remains highly empirical. Secondary dystonias, especially those related to specific drug treatment, have to be ruled out carefully. A few dystonic subgroups respond well to levodopa medication. In the other syndromes, anticholinergics are the usual first choice. In focal conditions botulinum toxin injections seem to be the most effective regimen, although there are only a few long-term studies. Surgical procedures are an ultimate option.
Key words
Dystonia Anticholinergics Botulinum toxin StereotaxyAbbreviations
- PET
positron emission tomography
- CT
computer tomography
- MRI
magnetic resonance imaging
- HIV
human immundeficiency virus
- EMG
electromyography
- AIDS
acquired immunodeficiency virus
- PTH
parathyroid hormone
- DMD
dystonia musculorum deformans
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References
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