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Infection

, Volume 4, Supplement 1, pp S71–S74 | Cite as

Pulmonary function in children withMycoplasma pneumoniae pneumonia

  • B. Kjellman
The Effects Of Mycoplasmal Infection On Respiratory Function

Summary

Nine children between the ages of seven to 12 were studied. All of these children had an acute unilateral pneumonia caused byMycoplasma pneumoniae. Regional pulmonary function studies were performed with the aid of an Xe133 radio-spirometry. It was shown with this technique that the ventilation of the infected part was more reduced than the perfusion during the acute stage. Fourteen to 22 days after the onset of the disease three children had normal chest X-rays but abnormalities of the pulmonary function tests. In one child this abnormal function persisted at the third follow-up some months later. By the use of regional pulmonary function studies subtle abnormalities can be observed which would normally be overlooked when examining the pulmonary function of both lungs.

Keywords

Alcuni Xe133 Leden Infected Part Onderzoek Naar 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Die Lungenfunktion bei Kindern mitMycoplasma-pneumoniae-Pneumonie

Zusammenfassung

Neun Kinder im Alter von sieben bis zwölf Jahren wurden untersucht. In allen Fällen lag akute einseitige Pneumonie vor, verursacht durchMycoplasma pneumoniae. Mittels133Xe-Radiospirometrie wurden regionale Lungenfunktionsprüfungen durchgeführt. Dabei zeigte sich, daß die Ventilation des infizierten Bereichs während des akuten Stadiums stärker herabgesetzt war als die Durchblutung. 14 bis 22 Tage nach Krankheitsausbruch war bei drei Kindern die Brustaufnahme normal, die Funktion des pneumonischen Bereiches dagegen noch pathologisch. In einem Fall war diese Funktion auch bei der dritten Nachuntersuchung einige Monate später noch pathologisch. Mit regionalen Lungenfunktionsprüfungen lassen sich auch geringfügige pathologische Veränderungen feststellen, die bei Funktionsprüfungen beider Lungen meistens übersehen werden.

Résumé

L'étude porte sur 9 enfants de 7 à 12 ans. Tous ces enfants présentaient une pneumonie aiguë unilatérale àM. pneumoniae. Des études de la fonction respiratoire régionale ont été réalisées par radiospirométrie au gaz xénon (133Xe). Cette méthode a permis de constater que la ventilation de la partie infectée étaient moins importante que la perfusion durant la phase aiguë. De 14 à 22 jours après le début de la maladie, 3 enfants présentaient une radiographie thoracique normale, mais une fonction pulmonaire anormale. Chez un enfant, cette anomalie de la fonction a persisté jusqu'au troisième contrôle plusieurs mois après. Le recours aux études de la fonction pulmonaire régionale a permis d'observer des anomalies subtiles qui échapperaient normalement à l'examen de la fonction pulmonaire bilatérale.

Resumen

Nueve niños entre 7 y 12 años de edad fueron estudiados. Todos ellos padecían una neumonía unilateral aguda debida alM. pneumoniae. Se realizaron estudios de la función pulmonar regional con la ayuda de un Xe133 de radio espirometría. Con esta técnica se demostró que la ventilación de la zona infectada fué más reducida que la perfusión durante el período agudo. De 14 a 22 dias después del comienzo de la enfermedad, 3 niños tenían un examen radiográfico normal, pero sin embargo presentaban una función anormal de la sección neumónica. En un niño, esta función anormal persistía al tercer „chequeo“ realizado unos meses más tarde. Con el uso de los estudios sobre la función pulmonar regional se pueden observar anormalidades sutiles, las cuales pasarían desapercibidas en un examen de la función pulmonar de ambos pulmones.

Samenvatting

Negen kinderen van 7 tot 12 jaar werden onderzocht. Al deze kinderen leden aan een acute unilaterale pneumonie veroorzaakt doorM. pneumoniae. Regionaalsgewijs longfunctie onderzoek werd verricht met behulp van Xe133 radio spirometrie. Er werd met deze techniek aangetoond, dat in het acute stadium de ventilatie van het geïnfecteerde deel sterker verminderd was dan de perfusie. 14 tot 22 dagen na het begin van de ziekte hadden 3 kinderen weer een normale X-thorax, doch een abnormale functie van het betrokken longdeel. Bij een kind bleef deze abnormale functie bestaan tot het derde vervolgonderzoek enige maanden later. Door gebruik te maken van onderzoek naar de longfunctie van longdelen kunnen subtiele afwijkingen worden waargenomen die normaal, bij het onderzoek van de functie van beide longen, onopgemerkt zouden blijven.

Riassunto

Furono studiati 9 ragazzi di età compresa tra 7–12 anni che presentavano tutti una polmonite acuta unilaterale daM. pneumoniae. Mediante una spirometria con Xe133 sono stati compiuti studi sulla funzionalità regionale del polmone. Mediante questa tecnica è stato dimostrato che la ventilazione della zona infetta era ridotta maggiormente che non la perfusione, durante la fase acuta. 14–22 giorni dopo la comparsa della malattia, 3 dei ragazzi presentavano un normale quadro radiologico ma la funzionalità della sezione polmonare era ancora anormale ed in un ragazzo tale anormalità persisteva ancora alcuni mesi più tardi. Anomalie lievi che normalmente sfuggirebbero all' esame della funzionalità di entrambi i polmoni possono essere evidenziate mediante l'uso di tecniche che permettono lo studio della funzione polmonare zonale.

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Copyright information

© Verlagsgesellschaft Otto Spatz 1976

Authors and Affiliations

  • B. Kjellman
    • 1
  1. 1.Department of Pediatrics Central HospitalSkövdeSweden

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