Blut

, Volume 23, Issue 5, pp 320–326 | Cite as

Anti-human lymphocyte globulin-(ALG-)sensitive lymphocyte populations in the blood of newborn premature infants, of older premature infants and of full-term newborn infants

A quantitative in-vitro study
  • G. Prindull
  • Brigitte Prindull
Article
Received:

Summary

The number of ALG-sensitive lymphocytes of the blood has been estimated quantitatively in cultures from premature and full-term newborn infants and from older premature infants studied at the time of their calculated birth dates. This was done by relating the total number of cultured cells and the number of transformed cells to the original number of blood lymphocytes with which the cultures had been set up.

The results were compared to those from comparable infant groups after PHA stimulation [15], and blood lymphocytes of these infants were characterized in terms of ALG-and PHA-sensitive populations.

Keywords

Public Health Premature Infant Blood Lymphocyte Newborn Infant Birth Date 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Die Anzahl ALG-sensibler Lymphozyten des Blutes wurde quantitativ in Kulturen von reifen und unreifen Neugeborenen und von älteren Frühgeborenen zum Zeitpunkt des errechneten Geburtstermins bestimmt. Dies wurde dadurch möglich, daß die Gesamtzellzahl und die Zahl der transformierten Zellen in den Kulturen auf die ursprüngliche Zahl der Blutlymphozyten, mit der die Kulturen angesetzt worden waren, bezogen wurden.

Die vorliegenden Ergebnisse und Ergebnisse vergleichbarer Untersuchungsgruppen nach PHA-Stimulierung [15] erlaubten es, die Blutlymphozytenpopulationen dieser Kinder im Hinblick auf ihre ALG-und PHA-Reaktivität zu charakterisieren.

This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literature

  1. 1.
    Averdunk, R.: Z. Naturforsch.25b, 510 (1970).Google Scholar
  2. 2.
    Bach, F. H., and M. L. Bach: Federat. Proc.29, 130 (1970).Google Scholar
  3. 3.
    David, H. A., H. O. Hartley and E. S. Pearson: Biometrika41, 482 (1954).Google Scholar
  4. 4.
    Doenhoff, M., H. Festenstein, E. Leuchars and A. J. S. Davies: Lancet1, 531 (1968).Google Scholar
  5. 5.
    Everett, N. B., M. R. Schwarz, R. W. Tyler and W. D. Perkins: Federat. Proc.29, 212 (1970).Google Scholar
  6. 6.
    Fries, D., P. A. Bryon, N. Brunat-Blanc, J. Brochier, M. Carraz and J. Traeger: Exp. Cell Res.54, 23 (1969).Google Scholar
  7. 7.
    Gräsbeck, R., C. T. Nordman and A. de la Chapelle: Acta med. scand. Suppl.412, 39 (1964).Google Scholar
  8. 8.
    Hirschhorn, K. in: Histocompatibility Testing, p. 177, publicat. No. 1229, Nat. Acad. Sci. Nat. Res. Council, Washington 1965.Google Scholar
  9. 9.
    Jones, G., E. C. Marcuson and I. M. Roitt: Nature [London]227, 1051 (1970).Google Scholar
  10. 10.
    Klein, E., T. Eskeland, M. Inoue and R. Storm: Exp. Cell Res.62, 133 (1970).Google Scholar
  11. 11.
    Ling, N. R., S. Knight, D. Hardy, D. R. Stanworth and P. J. L. Holt in: Antilymphocytic Serum, Ciba Found, Study Group No. 29, Churchill Ltd. G. E. W. Wolstenholme & M. O'Connor eds. London 1967.Google Scholar
  12. 12.
    Marcuson, E. C. and I. M. Roitt: Immunology16, 791 (1969).Google Scholar
  13. 13.
    McCarthy, M. J.: Ann. paediatrici (Basel)196, 204 (1961).Google Scholar
  14. 14.
    Möller, G.: Immunology19, 583 (1970).Google Scholar
  15. 15.
    Prindull, G.: Blut,23, 7 (1971).Google Scholar
  16. 16.
    Sachs, L.: Statistische Auswertungsmethoden, Springer-Verlag, Berlin 1968.Google Scholar
  17. 17.
    Simons, M. J., R. Fowler and M. G. Fitzgerald: Nature (London)219, 1021 (1968).Google Scholar
  18. 18.
    Tursi, A., M. F. Graeves, G. Torrigiani, J. H. Playfair and I. M. Roitt: Immunology17, 801 (1969).Google Scholar
  19. 19.
    Vincent, P. C. and F. W. Gunz: Lancet2, 342 (1970).Google Scholar
  20. 20.
    Warner, N. L. and P. Byrt: Nature (London)226, 942 (1970).Google Scholar

Copyright information

© J. F. Lehmanns Verlag 1971

Authors and Affiliations

  • G. Prindull
    • 1
  • Brigitte Prindull
    • 1
  1. 1.Universitäts-Kinderklinik GöttingenGöttingen

Personalised recommendations