Virchows Archiv A

, Volume 417, Issue 5, pp 443–447 | Cite as

Well-differentiated papillary mesothelioma of the peritoneum: A borderline mesothelioma

Report of two cases and review of literature
  • Karl-F Bürrig
  • Peter Pfitzer
  • Waldemar Hort
Case Report

Summary

Well-differentiated papillary mesothelioma (WDPM) is considered to be a distinct subtype of peritoneal mesothelioma. Although the WDPM is usually qualified as benign, the natural history of this lesion has not been clearly established. This report relates to two WDPMs which were found incidentally. In a 51-year-old man the WDPM developed over a period of 5 years into a typically malignant diffuse mesothelioma. Thus, although the WDPM morphologically lacks signs of malignancy, it should be regarded as a borderline mesothelioma.

Key words

Mesothelioma Pathology Ultrastructure Peritoneum 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Babera V, Rubino M (1957) Papillary mesothelioma of the tunica vaginalis. Cancer 10:183–189Google Scholar
  2. Bignon J, Sebastien P, Jaurand MD, Hem B (1974) Microfiltration method for quantitative study of fibrous particles in biological specimens. Environ Health Perspect 9:155–160Google Scholar
  3. Blobel GA, Moll R, Franke WW, Kayser KW, Gould VE (1985) The intermediate filament cytoskeleton of malignant mesotheliomas and its diagnostic significance. Am J Pathol 121:235–247Google Scholar
  4. Bolen JW, Hammar SP, McNutt MA (1986) Reactive and neoplastic serosal tissue. A light-microscopic, ultrastructural, and immunocytochemical study. Am J Surg Pathol 10:34–47Google Scholar
  5. Bollinger DJ, Wick MR, Dehner LP, Mills SE, Swanson PE, Clarke RE (1989) Peritoneal malignant mesothelioma versus serous papillary adenocarcinoma. A histochemical and immunohistochemical comparison. Am J Surg Pathol 13:659–670Google Scholar
  6. Bürrig KF (1988) Epithelial (true) splenic cysts. Pathogenesis of the mesothelial and so-called epidermoid cyst of the spleen. Am J Surg Pathol 12:275–281Google Scholar
  7. Foyle A, Al-Jabi M, McCaughey WTE (1981) Papillary peritoneal tumors in women. Am J Surg Pathol 5:241–249Google Scholar
  8. Goepel JR (1981) Benign papillary mesothelioma of peritoneum: a histological, histochemical and ultrastructural study of six cases. Histopathology 5:21–30Google Scholar
  9. Hanrahan JB (1963) A combined papillary mesothelioma and adenomatoid tumor of the omentum. Cancer 16:1497–1500Google Scholar
  10. Hellström PE, Friman C, Teppo L (1977) Malignant mesothelioma of 17 years duration with high pleural fluid concentrate of hyaluronate. Scand J Respir Dis 58:97–102Google Scholar
  11. Klima M, Györkey F (1977) Benign pleural lesions and malignant mesothelioma. Virchows Arch [A] 376:181–193Google Scholar
  12. McCaughey WTE (1985) Papillary peritoneal neoplasms in females. Pathol Annu 20:387–404Google Scholar
  13. McCaughey WTE, Kannerstein M, Churg J (1985) Tumors and pseudotumors of the serous membranes. Atlas of tumor pathology, 2nd series, fasc 20. AFIP, Washington, DCGoogle Scholar
  14. Möller P, Momburg F, Moldenhauer G (1986) Epitheliale Membranmarker — Bestandsaufnahme, eigene monoklonale Antikörper und aktuelle Möglichkeiten der Anwendung in der Histopathologie. Verh Dtsch Ges Pathol 70:116–126Google Scholar
  15. Pfaltz M, Odermatt B, Christen B, Rüttner JR (1987) Immunohistochemistry in the diagnosis of malignant mesothelioma. Virchows Arch [A] 411:387–393Google Scholar
  16. Rhind JA, Wright CJE (1939) Mesothelioma of the peritoneum. Report of a case and review of the literature. Br J Surg 35:359–363Google Scholar
  17. Roggli VL, Kolbeck J, Sanfilippo F, Shelburne JD (1987) Pathology of human mesothelioma. Etiologic and diagnostic considerations. Pathol Annu 22:91–131Google Scholar
  18. Wells AH (1935) Papillomatosis peritonei. Am J Pathol 11:1011–1013Google Scholar

Copyright information

© Springer-Verlag 1990

Authors and Affiliations

  • Karl-F Bürrig
    • 1
  • Peter Pfitzer
    • 2
  • Waldemar Hort
    • 1
  1. 1.Department of PathologyHeinrich-Heine-UniversityDüsseldorf 1Federal Republic of Germany
  2. 2.Department of CytologyHeinrich-Heine-UniversityDüsseldorfFederal Republic of Germany

Personalised recommendations