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Acta Neurochirurgica

, Volume 43, Issue 3–4, pp 229–237 | Cite as

The mode of mitochondrial degeneration in gliomas

  • C. S. Foster
  • P. E. Spoerri
  • P. Glees
  • O. Spoerri
Article

Summary

Morphologically abnormal mitochondria from human glial tumours are described. For each tumour both the appearances of the mitochondria, and the subsequent mode of degeneration and formation of osmiophilic pigment is characteristic.

The significance of these observations is discussed, and it is suggested that the mode of degeneration observed reflects directly a fundamental abnormality in composition compared to normal mitochondria.

Key words

Glioma mitochondria degeneration osmiophilic pigment 

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Copyright information

© Springer-Verlag 1978

Authors and Affiliations

  • C. S. Foster
    • 1
    • 2
  • P. E. Spoerri
    • 1
  • P. Glees
    • 1
  • O. Spoerri
    • 1
  1. 1.Institute of Histology and NeuroanatomyUniversity of Göttingen and Neurosurgical ClinicGöttingenGermany
  2. 2.Department of Experimental PathologyGeneral HospitalPlymouth, DevonEngland

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