, Volume 3, Issue 1, pp 75–84 | Cite as

Characterization of a TLvariant of a homozygous TL+ mouse lymphoma

  • Robert Hyman
  • Valerie Stallings


A homozygous antigen-loss variant for the TL antigen was isolated by immunoselectionin vitro. The variant expressed <0.01 the parental amount of TL antigen on its surface as measured by quantitative absorption. Neither theK nor theD end H-2k antigens were detectable on the surface of the variant, although parental amounts of Thy 1.2 and GCSA were expressed. Karyotypic analysis showed that the variant had one less chromosome than the parental line.


Lymphoma Parental Line Karyotypic Analysis Quantitative Absorption Parental Amount 
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Copyright information

© Springer-Verlag New York Inc. 1976

Authors and Affiliations

  • Robert Hyman
    • 1
  • Valerie Stallings
    • 1
  1. 1.Department of Cancer BiologyThe Salk Institute for Biological StudiesSan Diego

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