Journal of Industrial Microbiology

, Volume 17, Issue 5–6, pp 417–423 | Cite as

Taxol from fungal endophytes and the issue of biodiversity

  • GA Strobel
  • WM Hess
  • E. Ford
  • RS Sidhu
  • X Yang


Fungi represent one of the most understudied and diverse group of organisms. Commonly, these organisms make associations with higher life forms and may proceed to biochemically mimic the host organism. An excellent example of this is the anticancer drug, taxol, which had been previously supposed to occur only in the plant genusTaxus (yew). However, taxol has been reported in a novel endophytic fungus—Taxomyces andreanae, but also has been demonstrated to occur in a number of unrelated fungal endophytes includingPestalotia, Pestalotiopsis, Fusarium, Alternaria, Pithomyces, Monochaetia and others. Thus, this report presents information on the presence of taxol among disparate fungal genera, and uses these observations as an additional argument to support efforts to study fungal endophytes and preserve their associated host plants.


fungi mycology taxol Taxus 


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Copyright information

© Society for Industrial Microbiology 1996

Authors and Affiliations

  • GA Strobel
    • 1
  • WM Hess
    • 2
  • E. Ford
    • 1
  • RS Sidhu
    • 3
  • X Yang
    • 4
  1. 1.Department of Plant PathologyMontana State UniversityBozemanUSA
  2. 2.Department of Botany and Range ScienceBrigham Young UniversityProvo
  3. 3.Cytoclonal Pharmaceutics, IncDallas
  4. 4.Department of Chemistry and BiochemistryConcordia UniversityMontrealCanada

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