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Journal of Industrial Microbiology

, Volume 5, Issue 2–3, pp 113–123 | Cite as

Pharmaceuticals from cultured algae

  • Robert E. Schwartz
  • Charles F. Hirsch
  • David F. Sesin
  • James E. Flor
  • Michel Chartrain
  • Robert E. Fromtling
  • Guy H. Harris
  • Michael J. Salvatore
  • Jerrold M. Liesch
  • Katherine Yudin
Original Papers

Summary

An algae screening program, including cultured macroalgae, cultured cyanobacteria and cultured eukaryotic microalgae has been undertaken. Methods for the isolation, purification, preservation and cultivation of axenic cyanobacteria and eukaryotic cultures have been developed. Screening of these groups for biologically active components has lead to the isolation of pachydictyol and caulerpenyne from cultured macroalgae, while a series of hapalindoles and an antifungal depsipeptide have been isolated from cyanobacteria.

Key words

Cyanobacteria Eukaryotic microalgae Macroalgae Natural products Screening Pharmaceuticals 

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Copyright information

© Society for Industrial Microbiology 1990

Authors and Affiliations

  • Robert E. Schwartz
    • 2
  • Charles F. Hirsch
    • 2
  • David F. Sesin
    • 2
  • James E. Flor
    • 2
  • Michel Chartrain
    • 2
  • Robert E. Fromtling
    • 2
  • Guy H. Harris
    • 2
  • Michael J. Salvatore
    • 2
  • Jerrold M. Liesch
    • 2
  • Katherine Yudin
    • 1
  1. 1.Ocean Genetics, Inc.SantaU.S.A.
  2. 2.Merck, Sharp & Dohme Research LaboratoriesRahwayU.S.A.

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