Theczc operon ofAlcaligenes eutrophus CH34: from resistance mechanism to the removal of heavy metals
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The plasmid-borneczc operon ensures for resistance to Cd2+, Zn2+ and Co2+ ions through a tricomponent export pathway and is associated to various conjugative plasmids ofA. eutrophus strains isolated from metal-contaminated industrial areas. Theczc region of pMOL30 was reassessed especially for the segments located upstream and downstream the structural genesczc CBA. In cultures grown with high concentrations of heavy metals,czc-mediated efflux of cations is followed by a process of metal bioprecipitation. These observations led to the development of bioreactors designed for the removal of heavy metals from polluted effluents.
Key wordsSoil bacteria Alcaligenes Plasmid Cadmium Metal resistance Cation efflux Gene fusion Bioprecipitation Bioreactor
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