Advertisement

Journal of Industrial Microbiology

, Volume 1, Issue 6, pp 377–381 | Cite as

Effect of rare earth cations on bactericidal activity of anionic surfactants

  • R. W. Berg
  • R. E. Zimmerer
Original Papers

Summary

Rare earth metal cations are antibacterially synergistic with anionic surfactants, yielding mixtures that have bactericidal activity against a variety of gram-positive and gram-negative bacteria at minimum concentrations ranging from 16 to 125 μg/ml. Uptake of surfactant byEscherichia coli increases in the presence of lanthanum, suggesting that the role of rare earth metal cations is to reduce the net negative surface charge on the bacteria, thereby increasing the affinity between the negatively charged surfactant and the bacterial surface.

Key words

Antimicrobial Metal salt Lanthanum Escherichia coli Staphylococcus aureus 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Decad, G.M. and H. Nikaido. 1976. Outer membrane of gram-negative bacteria. XII. Molecular sieving function of cell wall. J. Bacteriol. 128: 325–336.PubMedGoogle Scholar
  2. 2.
    Dychdala, G.R. 1983. Surface active agents: acid-anionic compounds. In: Disinfection, Sterilization and Preservation, 3rd Edn. (Block, S.S., ed.), pp. 330–334. Lea & Febiger, Philadelphia.Google Scholar
  3. 3.
    Falk, I.S. 1928. Electrophoresis of bacteria and other micro-organisms and some relations to immunological theory. In: Colloid Chemistry, Vol. II (Alexander, J., ed.), pp. 731–746, The Chemical Catalog Company, Inc., New York.Google Scholar
  4. 4.
    Inouye, M. 1974. A three-dimensional molecular assembly model of lipoprotein from theEscherichia coli outer membrane. Proc. Natl. Acad. Sci. USA 71: 2396–2400.PubMedGoogle Scholar
  5. 5.
    Newton, B.A. 1960. The mechanism of the bactericidal action of surface active compounds: a summary. J. Appl. Bacteriol. 23: 345–349.Google Scholar
  6. 6.
    Nikaido, H., E.Y. Rosenberg and J. Foulds. 1983. Porin channels inEscherichia coli: studies with beta-lactams in intact cells. J. Bacteriol. 153: 232–240.PubMedGoogle Scholar
  7. 7.
    Payne, J.W. and C. Gilvarg. 1968. Size restriction in peptide utilization inEscherichia coli. J. Biol. Chem. 243: 6291–6299.PubMedGoogle Scholar
  8. 8.
    Petrocci, A.N. 1983. Surface active agents: quaternary ammonium compounds. In: Disinfection, Sterilization and Preservation, 3rd Edn. (Block, S.S., ed.), pp. 309–329, Lea & Febiger, Philadelphia.Google Scholar
  9. 9.
    Scherrer, R. and P. Gerhardt. 1971. Molecular sieving by theBacillus megaterium cell wall and protoplast. J. Bacteriol. 107: 718–735.PubMedGoogle Scholar
  10. 10.
    Smith, R.M. and A.E. Martell. 1976. Critical stability constants, Vol. 4. Plenum Press, New YorkGoogle Scholar
  11. 11.
    Stearn, A.E. and E.W. Stearn. 1931. Metathetic equilibria of bacterial systems with special reference to bacteriostasis and bacterial flocculation. Protoplasma 12: 435–464.Google Scholar
  12. 12.
    Voss, J.G. 1963. Effect of inorganic cations on bactericidal activity of anionic surfactants. J. Bacteriol. 86: 207–211.PubMedGoogle Scholar

Copyright information

© Society for Industrial Microbiology 1987

Authors and Affiliations

  • R. W. Berg
    • 1
  • R. E. Zimmerer
    • 1
  1. 1.The Procter and Gamble CompanyCincinnatiUSA

Personalised recommendations