International Journal of Biometeorology

, Volume 21, Issue 1, pp 64–74 | Cite as

The effects of acclimation to alternating environmental temperature on metabolic and endocrine responses in guinea pigs, during acute heat and cold exposure

  • I. Chowers
  • R. A. Siegel
  • N. Conforti
  • L. Baranes


Male Guinea pigs (n=80) were divided into four groups and maintained in a climatic chamber for three weeks in one of the following environmental conditions: (1) Ta20°C and 55% RH; (2) Ta35°C and 30–35% RH from 08:00 to 20:00 h and 5°C; 60–65% RH, from 20:00 h to 08:00 h; (3) Ta5°C and 60–65% RH; (4) Ta35°C and 30–35% RH. At the end of this period the animals were exposed to either −5°C, 60–65% RH or 45°C, 30–35% RH, for a period of 20 min, following which Tre, plasma 11-OHCS, thyroxin, glucose, and FFA, and body and organ weights were determined. The cold-warm adapted animals seemed to develop a more efficient adaptability to acute heat and cold exposure. It is suggested that on acute exposure to severe environmental conditions the endocrine and the nervous system play a dominant role in maintaining optimal body temperature, while on chronic exposure the metabolic rate of the various organs becomes relatively more important.


Glucose Body Temperature Metabolic Rate Dominant Role Thyroxin 
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Copyright information

© Swets & Zeitlinger B.V. 1977

Authors and Affiliations

  • I. Chowers
    • 1
  • R. A. Siegel
  • N. Conforti
  • L. Baranes
  1. 1.Department of Medicine ‘A’, Laboratory of Experimental Endocrinology and NeurologyHadassah University HospitalJerusalemIsrael

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